ArticleNature2024
Mapping genotypes to chromatin accessibility profiles in single cells.
Abstract read
In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed.
- MNS induces antiviral protection and suppresses inflammation.Annals of medicine · 2026Article
- Type 1 interferon perturbates clonal competition by reshaping human blood development.Nature genetics · 2026Article
- A single-cell lens into the co-evolution of genotypes and phenotypes in cancer.Nature reviews. Cancer · 2026Review
- Scalable genotyping in fixed transcriptomes resolves clonal heterogeneity via single-cell sequencing.bioRxiv : the preprint server for biology · 2026Article
- LOTR-Seq: A protocol for large-scale simultaneous single-cell long-read genotyping of transcripts.STAR protocols · 2026Article
- Clonal Metamorphosis: Deconstructing MPN Evolution with Single-Cell and Spatial Multi-Omics.Clinical and experimental medicine · 2026Review
- Article
- Article
- Charting single-cell lineages with synthetic and natural barcodes.Nature reviews. Genetics · 2026Review
- Single-cell epigenetic and transcriptomic states across the continuum of monoclonal B cell lymphocytosis to chronic lymphocytic leukemia.Genome biology · 2026Article
- Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia.Cancer discovery · 2026Article
- JAK2V617F reprograms Hypoxia Inducible Factor-1 to induce a non-canonical hypoxia regulon in myeloproliferative neoplasms.Leukemia · 2026Article
- Blood-based epigenetic instability linked to human aging and disease.Nature communications · 2026Article
- Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Dynamics of clonal hematopoiesis and cellular responses to stress-induced toxicity in autologous stem cell transplantation.Leukemia · 2026Article
- Co-mapping clonal and transcriptional heterogeneity in somatic evolution via GoT-Multi.Cell genomics · 2026Article
- Charting clonal evolution and behavior with GoT-Multi.Cell genomics · 2026Article
- Elevated P-RBC complexes are associated with thrombotic risk and diagnostic potential in myeloproliferative neoplasms: a retrospective cohort study.American journal of translational research · 2026Article
- Clinically oriented immune heterogeneity in prostate cancer: emerging targets and strategies.Frontiers in immunology · 2026Review
- scDNA: Single Cell DNA analysis software toolkit for subclonality discovery and assessment.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors.
Franco Izzo *New York Genome Center, New York, NY, USA. franco.izzo@mssm.edu.ORCID 0000-0002-5813-6504
Robert M Myers *New York Genome Center, New York, NY, USA.ORCID 0000-0003-1869-6467
Saravanan Ganesan *New York Genome Center, New York, NY, USA.
Levan Mekerishvili *New York Genome Center, New York, NY, USA.ORCID 0000-0002-4792-5356
Sanjay KottapalliNew York Genome Center, New York, NY, USA.
Tamara PrietoNew York Genome Center, New York, NY, USA.
Elliot O EtonNew York Genome Center, New York, NY, USA.ORCID 0000-0002-8980-9310
Theo BotellaNew York Genome Center, New York, NY, USA.
Andrew J DunbarMolecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Robert L BowmanMolecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jesus SoteloNew York Genome Center, New York, NY, USA.
Catherine PotenskiNew York Genome Center, New York, NY, USA.
Eleni P MimitouNew York Genome Center, New York, NY, USA.ORCID 0000-0001-9737-6394
Maximilian StahlMolecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sebastian El Ghaity-BeckleyDivision of Hematology/Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
JoAnn ArandelaDivision of Hematology/Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ramya RaviramNew York Genome Center, New York, NY, USA.
Daniel C ChoiLaboratory of Molecular Hematopoiesis, Hematology and Oncology, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0003-3406-9113
Ronald HoffmanDivision of Hematology/Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ronan ChalignéNew York Genome Center, New York, NY, USA.ORCID 0000-0003-4332-3291
Omar Abdel-WahabMolecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-3907-6171
Peter SmibertNew York Genome Center, New York, NY, USA.ORCID 0000-0003-0772-1647
Irene M GhobrialDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.ORCID 0000-0001-7361-3092
Joseph M ScanduraLaboratory of Molecular Hematopoiesis, Hematology and Oncology, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-9525-143X
Bridget MarcellinoDivision of Hematology/Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ross L LevineMolecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-7884-1905
Dan A LandauNew York Genome Center, New York, NY, USA. dlandau@nygenome.org.ORCID 0000-0003-2346-9541
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MTissue BankP01CA108671 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Ronald Hoffman · 2006 to 2026
$82.0MWeill Cornell/Rockefeller/Sloan-Kettering MST ProgramT32GM007739 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI HSU, KATHARINE C · 1985 to 2023
$51.1MCenter for Integrated Cellular Analysis - Valeria A. Sanchez EstradaRM1HG011014 · NHGRI · NEW YORK GENOME CENTER · PI LANDAU, DAN, SATIJA, RAHUL · 2020 to 2025
$22.1MThe Memorial Sloan Kettering Cancer Center SPORE in LeukemiaP50CA254838 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Eytan Stein · 2021 to 2026
$16.8MCharting the differentiation topology of SF3B1 mutated clonal hematopoiesis (CH) and myelodysplastic syndromes (MDS) via a multi-omics single-cell toolkitR01HL157387 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LANDAU, DAN · 2022 to 2025
$2.7MExpanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypesR33CA267219 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LANDAU, DAN · 2022 to 2024
$1.2MSingle-Cell Multi-omics to Link Clonal Mosaicism (CM) Genotypes with Chromatin, Epigenomic, Transcriptomic and Protein PhenotypesUG3NS132139 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI LANDAU, DAN, SATIJA, RAHUL · 2023 to 2024
$834kThe Role of PPM1D in Myeloproliferative NeoplasmsK08HL163489 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Bridget Kelly Marcellino · 2023 to 2026
$612kNCI NIH HHS P01 CA108671NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA254838NCI NIH HHS R33 CA267219NHGRI NIH HHS RM1 HG011014NHLBI NIH HHS K08 HL163489NHLBI NIH HHS R01 HL157387NIGMS NIH HHS T32 GM007739NINDS NIH HHS UG3 NS132139
Abstract
In somatic tissue differentiation, chromatin accessibility changes govern priming and precursor commitment towards cellular fates
Indexed as
ChromatinEpigenesis, GeneticGenotypeMutationSingle-Cell AnalysisAnimalsAntigens, CD34Cell DifferentiationClone CellsEpigenomeFemaleGenome, MitochondrialGenotyping TechniquesHematopoiesisHematopoietic Stem CellsHumansAntigens, CD34ChromatinJAK2 protein, humanJanus Kinase 2Membrane ProteinsRNA
Identifiers
What Socratic holds
Textmetadata
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.