Evidence map›Paper›PMID 38722176›Full record

ArticleJournal of bacteriology2024

Comparison of CcrM-dependent methylation in

Maxwell Campbell, Ian Scott Barton, R Martin Roop, Peter Chien

Abstract readComparative Study
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Inhibition ofACS omega · 2025
    Article
  2. Article
  3. Inhibition ofbioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Maxwell CampbellDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, Massachusetts, USA.ORCID 0009-0001-6352-0463
Ian Scott BartonDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, South Carolina, USA.
R Martin RoopDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, South Carolina, USA.ORCID 0000-0003-2101-6928
Peter ChienDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, Massachusetts, USA.ORCID 0000-0001-6733-1478

Funding

Regulated Proteolysisin Bacteria Development and Stress ResponseR35GM130320 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Peter Chien · 2019 to 2026
$3.4M
Determining the molecular basis of gene silencing by MucR and defining its role in Brucella virulenceR01AI172822 · NIAID · EAST CAROLINA UNIVERSITY · PI ROY M ROOP · 2023 to 2026
$2.3M
Role of a UPP-like exopolysaccharide in Brucella virulenceR21AI148132 · NIAID · EAST CAROLINA UNIVERSITY · PI ROOP, ROY M · 2020 to 2021
$401k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R21AI148132, R01AI172822HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM130320NIAID NIH HHS R01 AI172822NIAID NIH HHS R21 AI148132NIGMS NIH HHS R35 GM130320U.S. Department of Agriculture (USDA) USDA-NIFA 7002581
6 · The paper itself

Abstract

Bacteria rely on DNA methylation for restriction-modification systems and epigenetic control of gene expression. Here, we use direct detection of methylated bases by nanopore sequencing to monitor global DNA methylation in Alphaproteobacteria, where use of this technique has not yet been reported. One representative of this order,

Indexed as

Bacterial ProteinsBrucella abortusCaulobacter crescentusDNA MethylationGene Expression Regulation, BacterialNanopore SequencingDNA, BacterialSite-Specific DNA-Methyltransferase (Adenine-Specific)Bacterial ProteinsDNA, BacterialDNA modification methylase CcrMSite-Specific DNA-Methyltransferase (Adenine-Specific)BrucellaCaulobacterCcrMcell-cycleepigeneticsLonmethylationnanopore

Identifiers

PMID38722176
PMCPMC11332171

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.