Evidence map›Paper›PMID 38722677›Full record

ArticleeLife2024

Downregulation of

Phillip A Erice, Xinyan Huang, Matthew J Seasock, Matthew J Robertson, Hui-Ying Tung, Melissa A Perez-Negron, Shivani L Lotlikar, David B Corry, Farrah Kheradmand, Antony Rodriguez

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Phillip A EriceImmunology Graduate Program, Baylor College of Medicine, Houston, United States.
Xinyan HuangDepartment of Medicine, Immunology & Allergy Rheumatology, Baylor College of Medicine, Houston, United States.
Matthew J SeasockImmunology Graduate Program, Baylor College of Medicine, Houston, United States.ORCID https://orcid.org/0000-0002-5940-5913
Matthew J RobertsonDan Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, United States.
Hui-Ying TungDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, United States.
Melissa A Perez-NegronDepartment of Medicine, Immunology & Allergy Rheumatology, Baylor College of Medicine, Houston, United States.
Shivani L LotlikarDepartment of Medicine, Immunology & Allergy Rheumatology, Baylor College of Medicine, Houston, United States.
David B CorryDepartment of Medicine, Immunology & Allergy Rheumatology, Baylor College of Medicine, Houston, United States.
Farrah KheradmandDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, United States.
Antony RodriguezDepartment of Medicine, Immunology & Allergy Rheumatology, Baylor College of Medicine, Houston, United States.ORCID https://orcid.org/0000-0001-7184-9413

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Michael M Ittmann · 2007 to 2026
$73.9M
Initiative for Maximizing Student Development (IMSD) ProgramR25GM056929 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI PEREIRA, FRED A · 1998 to 2023
$12.4M
Training in Precision Environmental Health SciencesT32ES027801 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Cheryl L. Walker · 2018 to 2026
$2.8M
Role of Let-7 as genetic modifier of Alzheimer's DiseaseR01HL140398 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI CORRY, DAVID B, RODRIGUEZ, ANTONY · 2018 to 2022
$2.4M
Baylor College of Medicine Initiative for Maximizing Student DevelopmentT32GM152777 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI PANGAS, STEPHANIE A., PEREIRA, FRED A · 2024 to 2024
$547k
BD Biosciences Special Order LSRIIS10RR024574 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LUMPKIN, ELLEN A · 2009 to 2009
$430k
NCI NIH HHS P30 CA125123NCRR NIH HHS S10 RR024574NHLBI NIH HHS R01 HL140398NHLBI NIH HHS R01HL140398NIEHS NIH HHS T32 ES027801NIGMS NIH HHS R25 GM056929NIGMS NIH HHS T32 GM152777
6 · The paper itself

Abstract

Environmental air irritants including nanosized carbon black (nCB) can drive systemic inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema development. The

Indexed as

Cell DifferentiationDown-RegulationMicroRNAsNuclear Receptor Subfamily 1, Group F, Member 3Pulmonary EmphysemaTh17 CellsAnimalsFemaleHumansInterleukin-17LungMaleMiceMice, Inbred C57BLInterleukin-17MicroRNAsmirnlet7 microRNA, humanmirnlet7 microRNA, mouseNuclear Receptor Subfamily 1, Group F, Member 3Rorc protein, mouseCD8+ T cellsCOPDIL17immunologyinflammationlet-7Mirlet7miRNAmouseRORC

Identifiers

PMID38722677
PMCPMC11081633

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.