Evidence map›Paper›PMID 38724025›Full record

ReviewAnnual review of cell and developmental biology2024

What Is a Plant Cell Type in the Age of Single-Cell Biology? It's Complicated.

Byron Rusnak, Frances K Clark, Batthula Vijaya Lakshmi Vadde, Adrienne H K Roeder

Abstract readReview
In one paragraph

Review in Annual review of cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Brassinosteroids mediate proper coordination of sepal elongation.bioRxiv : the preprint server for biology · 2025
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Byron RusnakWeill Institute for Cell and Molecular Biology and School of Integrative Plant Science, Section of Plant Biology, Cornell University, Ithaca, New York, USA; email: bzr5@cornell.edu, fkc6@cornell.edu, ahr75@cornell.edu.
Frances K ClarkDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA.
Batthula Vijaya Lakshmi VaddePlant Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, USA; email: vbattala@salk.edu.
Adrienne H K RoederWeill Institute for Cell and Molecular Biology and School of Integrative Plant Science, Section of Plant Biology, Cornell University, Ithaca, New York, USA; email: bzr5@cornell.edu, fkc6@cornell.edu, ahr75@cornell.edu.

Funding

Mechanisms of robustness in organogenesis (Equipment Supplement 2023)R01GM134037 · NIGMS · CORNELL UNIVERSITY · PI ROEDER, ADRIENNE H · 2020 to 2023
$1.5M
NIGMS NIH HHS R01 GM134037
6 · The paper itself

Abstract

One of the fundamental questions in developmental biology is how a cell is specified to differentiate as a specialized cell type. Traditionally, plant cell types were defined based on their function, location, morphology, and lineage. Currently, in the age of single-cell biology, researchers typically attempt to assign plant cells to cell types by clustering them based on their transcriptomes. However, because cells are dynamic entities that progress through the cell cycle and respond to signals, the transcriptome also reflects the state of the cell at a particular moment in time, raising questions about how to define a cell type. We suggest that these complexities and dynamics of cell states are of interest and further consider the roles signaling, stochasticity, cell cycle, and mechanical forces play in plant cell fate specification. Once established, cell identity must also be maintained. With the wealth of single-cell data coming out, the field is poised to elucidate both the complexity and dynamics of cell states.

Indexed as

Plant CellsSingle-Cell AnalysisCell CycleCell DifferentiationCell LineagePlantsSignal TransductionTranscriptomeArabidopsis thalianacell fatecell identity maintenancelineage versus positionmechanical stressscRNA-seqstochasticity

Identifiers

PMID38724025
PMCPMC12279474

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.