Evidence map›Paper›PMID 38726426›Full record

ArticleFood science & nutrition2024

A mixture of extracts from natural ingredients reduces the neurotoxic polarization of microglia via modulating NF-κB/NF-E2-related factor 2 activation.

Shuge Gui, Junjun Ni, Shinsuke Mizutani, Norihiro Shigematsu, Hiroshi Nakanishi, Haruhiko Kashiwazaki, Zhou Wu

Abstract read
In one paragraph

Article in Food science & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Lipopolysaccharides fromJournal of Alzheimer's disease : JAD · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuge GuiDepartment of Oral and Maxillofacial Surgery, Faculty of Dental Science Kyushu University Fukuoka Japan.ORCID https://orcid.org/0009-0004-3966-1102
Junjun NiKey Laboratory of Molecular Medicine and Biotherapy, School of Life Science Beijing Institute of Technology Beijing China.ORCID https://orcid.org/0000-0001-8486-8146
Shinsuke MizutaniSection of Geriatric Dentistry and Perioperative Medicine in Dentistry, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science Kyushu University Fukuoka Japan.
Norihiro ShigematsuYamada Institute for Health Science, R & D Department Yamada Bee Company, Inc. Okayama Japan.
Hiroshi NakanishiDepartment of Pharmacology, Faculty of Pharmacy Yasuda Women's University Hiroshima Japan.
Haruhiko KashiwazakiSection of Geriatric Dentistry and Perioperative Medicine in Dentistry, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science Kyushu University Fukuoka Japan.
Zhou WuDepartment of Aging Science and Pharmacology, Faculty of Dental Science Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0002-4910-9037

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurotoxic microglia-provoked neuroinflammation is implicated in cognitive decline in Alzheimer's disease (AD). Supplementation with

Indexed as

microglial polarizationnatural ingredientsNF‐E2‐related factor 2NF‐κB

Identifiers

PMID38726426
PMCPMC11077187

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.