Evidence map›Paper›PMID 38726468›Full record

ArticleJournal of the American College of Emergency Physicians open2024

Influence of time-to-diagnosis on time-to-percutaneous coronary intervention for emergency department ST-elevation myocardial infarction patients: Time-to-electrocardiogram matters.

Maame Yaa A B Yiadom, Wu Gong, Brian W Patterson, Christopher W Baugh, Angela M Mills, Nicholas Gavin, Seth R Podolsky, Bryn E Mumma, Mary Tanski, Gilberto Salazar and 7 more

Abstract read
In one paragraph

Article in Journal of the American College of Emergency Physicians open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Maame Yaa A B YiadomDepartment of Emergency Medicine Stanford University Stanford California USA.ORCID https://orcid.org/0000-0002-6479-0764
Wu GongDepartment of Biostatistics, Vanderbilt University Medical Center Nashville Tennessee USA.
Brian W PattersonDepartment of Emergency Medicine University of Wisconsin School of Medicine and Public Health Madison Wisconsin USA.
Christopher W BaughDepartment of Emergency Medicine Brigham and Women's Hospital-Harvard University Boston Massachusetts USA.
Angela M MillsDepartment of Emergency Medicine Columbia University College of Physicians and Surgeons New York New York USA.
Nicholas GavinDepartment of Emergency Medicine Icahn School of Medicine at Mount Sinai New York New York USA.
Seth R PodolskyLegacy Health Portland Oregon USA.
Bryn E MummaDepartment of Emergency Medicine University of California-Davis Davis California USA.
Mary TanskiDepartment of Emergency Medicine Oregon Health & Science University Portland Oregon USA.
Gilberto SalazarDepartment of Emergency Medicine University of Texas Southwestern Dallas Texas USA.
Caitlin AzzoDepartment of Emergency Medicine Massachusetts General Hospital, Harvard School of Medicine Boston Massachusetts USA.
Stephen C DornerDepartment of Emergency Medicine Massachusetts General Hospital, Harvard School of Medicine Boston Massachusetts USA.
Kelsea HadleySchool of Medicine American University of Antigua Osbourn Antigua and Barbuda.
Sean M BloosDepartment of Emergency Medicine Stanford University Stanford California USA.
Gabrielle BunneyDepartment of Emergency Medicine Stanford University Stanford California USA.
Timothy J VogusOwen Graduate School of Management Vanderbilt University Nashville Tennessee USA.
Dandan LiuDepartment of Biostatistics, Vanderbilt University Medical Center Nashville Tennessee USA.

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
The Vanderbilt Emergency Medicine Research Training Program (VEMRT)K12HL109019 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COLLINS, SEAN PATRICK, STORROW, ALAN B · 2011 to 2015
$3.7M
Using Predictive Modeling for Acute Coronary Syndrome Screening to Improve Timely Diagnosis and Mortality for STEMIR01HL171403 · NHLBI · STANFORD UNIVERSITY · PI Maame Yaa A.B. Yiadom · 2024 to 2026
$2.1M
Improving the Screening Criteria that Trigger an Early ECG to Diagnose STEMIK23HL133477 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI YIADOM, MAAME YAA A.B. · 2017 to 2019
$460k
NCATS NIH HHS UL1 TR000445NHLBI NIH HHS K12 HL109019NHLBI NIH HHS K23 HL133477NHLBI NIH HHS R01 HL171403
6 · The paper itself

Abstract

Objectives: Earlier electrocardiogram (ECG) acquisition for ST-elevation myocardial infarction (STEMI) is associated with earlier percutaneous coronary intervention (PCI) and better patient outcomes. However, the exact relationship between timely ECG and timely PCI is unclear. Methods: We quantified the influence of door-to-ECG (D2E) time on ECG-to-PCI balloon (E2B) intervention in this three-year retrospective cohort study, including patients from 10 geographically diverse emergency departments (EDs) co-located with a PCI center. The study included 576 STEMI patients excluding those with a screening ECG before ED arrival or non-diagnostic initial ED ECG. We used a linear mixed-effects model to evaluate D2E's influence on E2B with piecewise linear terms for D2E times associated with time intervals designated as ED intake (0-10 min), triage (11-30 min), and main ED (>30 min). We adjusted for demographic and visit characteristics, past medical history, and included ED location as a random effect. Results: The median E2B interval was longer (76 vs 68 min, Conclusion: Reducing D2E is associated with a shorter E2B. Targeting D2E reduction in patients currently diagnosed during triage (11-30 min) may be the greatest opportunity to improve D2B and could enable 24.9% more ED STEMI patients to achieve timely D2E.

Indexed as

door‐to‐balloon timedoor‐to‐ECGelectrocardiogrampercutaneous coronary interventionSTEMI

Identifiers

PMID38726468
PMCPMC11079543

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.