Evidence map›Paper›PMID 38726865›Full record

ArticleAutophagy2024

SCF

Yupei Liang, Ping Chen, Shiwen Wang, Lili Cai, Feng Zhu, Yanyu Jiang, Lihui Li, Lihua Zhu, Yongqing Heng, Wenjuan Zhang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Autophagy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. The structure and function of FBXW5 in human diseases.Biochemistry and biophysics reports · 2025
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yupei LiangCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Ping ChenSchool of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
Shiwen WangDepartment of Laboratory Medicine, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Lili CaiCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Feng ZhuDepartment of Laboratory Medicine, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Yanyu JiangCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Lihui LiCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Lihua ZhuCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yongqing HengDepartment of Integrative Medicine, Shanghai Pulmonary Hospital, Tongji University, Shanghai, China.
Wenjuan ZhangDepartment of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, Shanghai, China.
Yongfu PanCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wenyi WeiDepartment of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Lijun JiaCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AQP3 (aquaporin 3 (Gill blood group)), a member of the AQP family, is an aquaglyceroporin which transports water, glycerol and small solutes across the plasma membrane. Beyond its role in fluid transport, AQP3 plays a significant role in regulating various aspects of tumor cell behavior, including cell proliferation, migration, and invasion. Nevertheless, the underlying regulatory mechanism of AQP3 in tumors remains unclear. Here, for the first time, we report that AQP3 is a direct target for ubiquitination by the SCF

Indexed as

3-Phosphoinositide-Dependent Protein KinasesAquaporin 3AutophagyCarcinoma, HepatocellularF-Box ProteinsLiver NeoplasmsProto-Oncogene Proteins c-aktSignal TransductionTOR Serine-Threonine KinasesAnimalsCell Line, TumorHumansLysosomesProteolysisUbiquitination3-Phosphoinositide-Dependent Protein KinasesAQP3 protein, humanAquaporin 3F-Box ProteinsMTOR protein, humanPDPK1 protein, humanProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesAQP3autophagic cell deathFBXW5hepatocellular carcinomaPDPK1-AKT-MTOR pathway

Identifiers

PMID38726865
PMCPMC11346525

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.