Evidence map›Paper›PMID 38727539›Full record

ArticleBrain injury2024

Effects of mTBI with loss of consciousness on neurobehavioral symptoms, depression, and insomnia in former collegiate and NFL football athletes.

Sarah Laskowitz, C Lexi Baird, Ashley Huggins, Nino Nadareishvili, Jessica Bride, H Ryan Wagner, Melvin Briggs, Rajendra A Morey, Robert W Turner

Abstract read
In one paragraph

Article in Brain injury, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah LaskowitzBrain Imaging and Analysis Center, Duke University Medical Center, Durham, North Carolina, USA.
C Lexi BairdBrain Imaging and Analysis Center, Duke University Medical Center, Durham, North Carolina, USA.
Ashley HugginsDepartment of Psychology, The University of Arizona, Tucson, Arizona, USA.
Nino NadareishviliSchool of Medicine and Health Sciences, Department of Clinical Research and Leadership, George Washington University, Washington, District of Columbia, USA.
Jessica BrideSchool of Medicine and Health Sciences, Department of Clinical Research and Leadership, George Washington University, Washington, District of Columbia, USA.
H Ryan WagnerDepartment of Psychiatry, Duke University Medical Center, Durham, North Carolina, USA.
Melvin BriggsBrain Imaging and Analysis Center, Duke University Medical Center, Durham, North Carolina, USA.
Rajendra A MoreyDepartment of Psychiatry, Duke University Medical Center, Durham, North Carolina, USA.
Robert W TurnerDepartment of Clinical Research & Leadership, School of Medicine & Health Sciences, The George Washington University, Washington, USA.

Funding

The Contributions of Repetitive Head Impacts and Early Life Contextual Risk Factors to Alzheimer’s Disease and Related Dementias in Older Adult Black MenR01NS134043 · NINDS · GEORGE WASHINGTON UNIVERSITY · PI Robert W. Turner · 2023 to 2026
$3.8M
Black Male Dementia Caregiver Burden: Stress-related Cognitive Dysfunction, and physiological and psychosocial measuresK01AG054762 · NIA · GEORGE WASHINGTON UNIVERSITY · PI TURNER, ROBERT W. · 2017 to 2022
$832k
Mapping Subject-Specific Structural and Functional Connectivity to Parse the Unique Contributions of Subconcussive Blast, Mild TBI, and PTSDI01CX002293 · VA · DURHAM VA MEDICAL CENTER · PI RAJENDRA A MOREY · 2021 to 2026
–
CSRD VA I01 CX002293NIA NIH HHS K01 AG054762NINDS NIH HHS R01 NS134043
6 · The paper itself

Abstract

objectiveConsidering that diagnostic decisions about mTBI are often predicated on clinical symptom criteria, it is imperative to determine which initial presentation features of mTBI have prognostic significance for identifying those at high risk for long-term functional impairment.

settingZoom interview Participants: Male, former NCAA Division I, and professional-level National Football League (NFL) athletes (

designCross-sectional case-control. Main Measures: History of mild TBI, history of loss of consciousness (LOC), depression symptoms, insomnia, neurobehavioral symptoms.

resultsNumber of mTBI exposures did not predict neurobehavioral symptoms (B = 0.21, SE = 0.18,

conclusionsFindings support LOC at time of injury as an important predictor of long-term outcomes. Additionally, results suggest depression and insomnia as potential mediators in the association between mTBI + LOC and neurobehavioral symptoms. These findings provide justification for early depression and insomnia symptom monitoring following mTBI + LOC.

Indexed as

AthletesDepressionFootballSleep Initiation and Maintenance DisordersUnconsciousnessAdultAgedAged, 80 and overAthletic InjuriesBrain ConcussionCase-Control StudiesCross-Sectional StudiesHumansMaleMiddle AgedUniversitiesAmerican Footballdepressioninsomnialoss of consciousnessMild traumatic brain injuryneurobehavioral symptoms

Identifiers

PMID38727539
PMCPMC11323146

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.