SynthesisClinical oral investigations2024
Association between periodontitis and dental caries: a systematic review and meta-analysis.
Synthesis in Clinical oral investigations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Deep Learning for Detecting Dental Plaque and Gingivitis From Oral Photographs: A Systematic Review.Community dentistry and oral epidemiology · 2025Pooled it
- The Oral Virome in Dental Caries: From Ecological Disruptors to Therapeutic Opportunities.Journal of microbiology and biotechnology · 2026Review
- From Caries to Periodontal Breakdown: A Biological and Clinical Continuum Linking Cariology, Operative Dentistry, Endodontics, and Periodontology.Dentistry journal · 2026Review
- Construction and validation of oral frailty risk assessment model in elderly hospitalized patients.BMC oral health · 2026Article
- Oral health status and access to oral healthcare among adult refugees in Egypt: a cross-sectional study.BMC oral health · 2026Article
- The Interplay Between Periodontitis, Caries and Dental Restorations in an Adult Population.Journal of clinical periodontology · 2026Article
- Biosensors in dental, oral and craniofacial applications.Npj biosensing · 2026Review
- Four-Year Longitudinal Epidemiological Study on the Association Between a Multi-Item Saliva Testing System and Oral and Gut Microbiota.Microorganisms · 2025Article
- Asiatic Acid Disrupts the Biofilm Virulence ofInternational journal of molecular sciences · 2025Article
- Caries status influence GCF MMP-9 in association with serum vitamin D: an exploratory retrospective cross-sectional study.BMC oral health · 2025Article
- Association Between Ethylene Oxide Exposure and Complete Edentulism in United States Adults.Life (Basel, Switzerland) · 2025Article
- Association of 41 Inflammatory Cytokines With Common Oral Diseases.International dental journal · 2025Article
- Review
- Antimicrobial efficacy and cytotoxicity of ethanolic extracts ofJournal of advanced periodontology & implant dentistry · 2025Article
- Identification of Risk Group for Root Caries and Analysis of Associated Factors in Older Adults Using Unsupervised Machine Learning Clustering.Clinical interventions in aging · 2025Article
- The impact ofFrontiers in dental medicine · 2025Article
- Microbiome in Early Childhood Caries: Caries Severity-Dependent Insights.Caries research · 2025Article
- Association between periodontal disease and systemic diseases: a cross-sectional analysis of current evidence.Military Medical Research · 2024Article
- The convergence of artificial intelligence and robotics in precise dental plaque management.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2024Article
- Oral Prevalence ofPathogens (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesRecent evidence suggested a link between periodontitis (PD) and dental caries, but the trends and nature of this association remained unclear. The overall aim of this study was to critically assess the correlation of two disorders.
methodsA comprehensive search was conducted within the PUBMED and EMBASE databases including grey literatures up to July 5th, 2023. The Newcastle-Ottawa scale was used to qualitatively evaluate the risk of bias.
resultsOverall, 18 studies were included. In terms of caries risk in PD patients, the prevalence of caries was increased by PD (OR = 1.57, 95%CI:1.20-2.07), both in crown (OR = 1.03, 95%CI:1.01-1.05) and root caries (OR = 2.10, 95%CI:1.03-4.29). Odds of caries were also raised by PD severity (OR
conclusionsThis study indicated a positive correlation between dental caries and periodontitis clinically, while the two disease-associated pathogens were antagonistic. CLINICAL RELEVANCE: Further research, including clinical cohort studies and mechanisms of pathogens interaction is needed on this link for better prevention and treatment of PD and caries. In addition, innovative prevention strategies need to be developed and incorporated in dental practices to prevent these two highly prevalent oral diseases.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.