Evidence map›Paper›PMID 38727776›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2025

Costs associated with insufficient physical activity in Germany: cross-sectional results from the baseline examination of the German national cohort (NAKO).

Sophie Gottschalk, Hans-Helmut König, Andrea Weber, Michael F Leitzmann, Michael J Stein, Annette Peters, Claudia Flexeder, Lilian Krist, Stefan N Willich, Katharina Nimptsch and 16 more

Abstract read
In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Review
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  4. Review
  5. Economic cost of movement behaviours: a systematic review.Journal of activity, sedentary and sleep behaviors · 2026
    Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Sophie GottschalkDepartment of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany. s.gottschalk@uke.de.ORCID http://orcid.org/0000-0002-6912-6256
Hans-Helmut KönigDepartment of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0001-5711-6862
Andrea WeberDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.ORCID http://orcid.org/0000-0002-4777-7808
Michael F LeitzmannDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.ORCID http://orcid.org/0000-0002-0371-2789
Michael J SteinDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.ORCID http://orcid.org/0000-0002-1120-1751
Annette PetersInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health (GmbH), Neuherberg, Germany.ORCID http://orcid.org/0000-0001-6645-0985
Claudia FlexederInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health (GmbH), Neuherberg, Germany.ORCID http://orcid.org/0000-0003-3974-1482
Lilian KristInstitute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-6089-5163
Stefan N WillichInstitute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Katharina NimptschMolecular Epidemiology Research Group, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.ORCID http://orcid.org/0000-0001-7877-205X
Tobias PischonMolecular Epidemiology Research Group, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.
Sylvia GastellNAKO Study Center, German Institute of Human Nutrition Potsdam-Rehbruecke, Potsdam-Rehbruecke, Germany.ORCID http://orcid.org/0000-0003-2607-2400
Karen SteindorfDivision of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID http://orcid.org/0000-0001-5215-5651
Florian HerbolsheimerDivision of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID http://orcid.org/0000-0002-2137-4082
Nina EbertInstitute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany.
Karin B MichelsInstitute for Prevention and Cancer Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Anja DorrnInstitute for Prevention and Cancer Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Volker HarthInstitute for Occupational and Maritime Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nadia ObiInstitute for Occupational and Maritime Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0002-0903-9142
André KarchInstitute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.
Henning TeismannInstitute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.ORCID http://orcid.org/0000-0001-5807-5572
Henry VölzkeInstitute for Community Medicine, Department SHIP/ Clinical-Epidemiological Research, University Medicine Greifswald, Greifswald, Germany.ORCID http://orcid.org/0000-0001-7003-399X
Claudia Meinke-FranzeInstitute for Community Medicine, Department SHIP/ Clinical-Epidemiological Research, University Medicine Greifswald, Greifswald, Germany.ORCID http://orcid.org/0000-0001-6137-9702
Leon KlimeckDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID http://orcid.org/0009-0003-3607-3498
Teresa L SeumDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID http://orcid.org/0009-0003-4475-0583
Judith DamsDepartment of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInsufficient physical activity (PA) is a leading risk factor for non-communicable diseases posing a significant economic burden to healthcare systems and societies. The study aimed to examine the differences in healthcare and indirect costs between sufficient and insufficient PA and the cost differences between PA intensity groups.

methodsThe cross-sectional analysis was based on data from 157,648 participants in the baseline examination of the German National Cohort (NAKO) study. Healthcare and indirect costs were calculated based on self-reported information on health-related resource use and productivity losses. PA in the domains leisure, transport, and work was assessed by the Global Physical Activity Questionnaire and categorized into sufficient/insufficient and intensity levels (very low/low/medium/high) based on PA recommendations of the World Health Organization. Two-part models adjusted for relevant covariates were used to estimate mean costs for PA groups. RESULTS AND

conclusionInsufficiently active people had higher average annual healthcare costs (Δ €188, 95% CI [64, 311]) and healthcare plus indirect costs (Δ €482, 95% CI [262, 702]) compared to sufficiently active people. The difference was especially evident in the population aged 60 + years and when considering only leisure PA. An inverse association was observed between leisure PA and costs, whereas a direct association was found between PA at work and costs. Adjusting for the number of comorbidities reduced the differences between activity groups, but the trend persisted. The association between PA and costs differed in direction between PA domains. Future research may provide further insight into the temporal relationship between PA and costs.

Indexed as

ExerciseHealth Care CostsHealth ExpendituresAdultAgedCost of IllnessCross-Sectional StudiesFemaleGermanyHumansLeisure ActivitiesMaleMiddle AgedSurveys and QuestionnairesCohort studyExerciseHealthcare costsHealth expenditurePhysical activity

Identifiers

PMID38727776
PMCPMC11743391

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.