Evidence map›Paper›PMID 38730621›Full record

ArticleCancers2024

Germline Genetic Mutations in Adult Patients with Sarcoma: Insight into the Middle East Genetic Landscape.

Ramiz Abu-Hijlih, Baha Sharaf, Samer Salah, Hira Bani Hani, Mohammad Alqaisieh, Abdulla Alzibdeh, Layan Ababneh, Suleiman Mahafdah, Hikmat Abdel-Razeq

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ramiz Abu-HijlihDepartment of Radiation Oncology, King Hussein Cancer Center, Amman 11941, Jordan.ORCID 0000-0001-5397-6267
Baha SharafDepartment of Internal Medicine, King Hussein Cancer Center, Amman 11941, Jordan.ORCID 0000-0003-4368-1224
Samer SalahDepartment of Internal Medicine, King Hussein Cancer Center, Amman 11941, Jordan.
Hira Bani HaniDepartment of Internal Medicine, King Hussein Cancer Center, Amman 11941, Jordan.ORCID 0009-0001-3604-0886
Mohammad AlqaisiehDepartment of Internal Medicine, King Hussein Cancer Center, Amman 11941, Jordan.
Abdulla AlzibdehDepartment of Radiation Oncology, King Hussein Cancer Center, Amman 11941, Jordan.ORCID 0000-0002-4962-8398
Layan AbabnehSchool of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Suleiman MahafdahDepartment of Surgery, Royal Jordanian Medical Services, Amman 11855, Jordan.
Hikmat Abdel-RazeqDepartment of Internal Medicine, King Hussein Cancer Center, Amman 11941, Jordan.ORCID 0000-0003-2833-6051

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data on germline mutations in soft tissue and bone sarcomas are scarce. We sought to identify the prevalence of germline mutations in adult sarcoma patients treated at a tertiary cancer center. Newly diagnosed patients were offered germline genetic testing via an 84-gene panel. The prevalence of pathogenic germline variants (PGVs) and their association with disease-, and patient- related factors are reported. A total of 87 patients were enrolled, the median age was 48 (19-78) years, and 47 (54%) were females. Gastrointestinal stromal tumors (

Indexed as

osteosarcomapathogenic germline variantssarcomasoft tissue sarcoma

Identifiers

PMID38730621
PMCPMC11083501

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.