Evidence map›Paper›PMID 38730845›Full record

ArticleMaterials (Basel, Switzerland)2024

Dynamics of Dental Enamel Surface Remineralization under the Action of Toothpastes with Substituted Hydroxyapatite and Birch Extract.

Cristina Teodora Dobrota, Alexandra-Diana Florea, Csaba-Pal Racz, Gheorghe Tomoaia, Olga Soritau, Alexandra Avram, Horea-Rares-Ciprian Benea, Cristina Lavinia Rosoiu, Aurora Mocanu, Sorin Riga and 2 more

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cristina Teodora DobrotaResearch Center of Excellence in Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos St., 400028 Cluj-Napoca, Romania.ORCID 0000-0001-7676-6895
Alexandra-Diana FloreaResearch Center of Excellence in Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos St., 400028 Cluj-Napoca, Romania.ORCID 0000-0003-4054-972X
Csaba-Pal RaczResearch Center of Excellence in Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos St., 400028 Cluj-Napoca, Romania.
Gheorghe TomoaiaDepartment of Orthopedics and Traumatology, Iuliu Hatieganu University of Medicine and Pharmacy, 47 General Traian Mosoiu St., 400132 Cluj-Napoca, Romania.
Olga SoritauOncology Institute of Cluj-Napoca, 34-36 Republicii St., 400015 Cluj-Napoca, Romania.ORCID 0000-0002-9270-8529
Alexandra AvramResearch Center of Excellence in Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos St., 400028 Cluj-Napoca, Romania.
Horea-Rares-Ciprian BeneaDepartment of Orthopedics and Traumatology, Iuliu Hatieganu University of Medicine and Pharmacy, 47 General Traian Mosoiu St., 400132 Cluj-Napoca, Romania.
Cristina Lavinia RosoiuDepartment of Molecular Biology and Biotechnology, Faculty of Biology and Geology, Babeş-Bolyai University, 44 Republicii St., 400015 Cluj-Napoca, Romania.
Aurora MocanuResearch Center of Excellence in Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos St., 400028 Cluj-Napoca, Romania.
Sorin RigaResearch Center of Excellence in Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos St., 400028 Cluj-Napoca, Romania.
Attila-Zsolt KunResearch Center of Excellence in Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos St., 400028 Cluj-Napoca, Romania.
Maria Tomoaia-CotiselResearch Center of Excellence in Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany Janos St., 400028 Cluj-Napoca, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address tooth enamel demineralization resulting from factors such as acid erosion, abrasion, and chronic illness treatments, it is important to develop effective daily dental care products promoting enamel preservation and surface remineralization. This study focused on formulating four toothpastes, each containing calcined synthetic hydroxyapatite (HAP) in distinct compositions, each at 4%, along with 1.3% birch extract. Substitution elements were introduced within the HAP structure to enhance enamel remineralization. The efficacy of each toothpaste formulation was evaluated for repairing enamel and for establishing the dynamic of the remineralization. This was performed by using an in vitro assessment of artificially demineralized enamel slices. The structural HAP features explored by XRD and enamel surface quality by AFM revealed notable restorative properties of these toothpastes. Topographic images and the self-assembly of HAP nanoparticles into thin films on enamel surfaces showcased the formulations' effectiveness. Surface roughness was evaluated through statistical analysis using one-way ANOVA followed by post-test Bonferroni's multiple comparison test with a

Indexed as

AFMcalcined substituted hydroxyapatitesenamelremineralizationroughness and statistical analysistoothpastesXRD

Identifiers

PMID38730845
PMCPMC11084803

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.