Evidence map›Paper›PMID 38731837›Full record

ArticleInternational journal of molecular sciences2024

Development of a New Model System to Study Long-Distance Interactions Supported by Architectural Proteins.

Larisa Melnikova, Varvara Molodina, Pavel Georgiev, Anton Golovnin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Larisa MelnikovaDepartment of Drosophila Molecular Genetics, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, Moscow 119334, Russia.
Varvara MolodinaDepartment of Drosophila Molecular Genetics, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, Moscow 119334, Russia.
Pavel GeorgievDepartment of the Control of Genetic Processes, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, Moscow 119334, Russia.ORCID 0000-0002-6509-3194
Anton GolovninDepartment of Drosophila Molecular Genetics, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, Moscow 119334, Russia.

Funding

Russian Science Foundation 22-24-00719
6 · The paper itself

Abstract

Chromatin architecture is critical for the temporal and tissue-specific activation of genes that determine eukaryotic development. The functional interaction between enhancers and promoters is controlled by insulators and tethering elements that support specific long-distance interactions. However, the mechanisms of the formation and maintenance of long-range interactions between genome regulatory elements remain poorly understood, primarily due to the lack of convenient model systems.

Indexed as

Drosophila ProteinsEnhancer Elements, GeneticPromoter Regions, GeneticAnimalsBinding SitesChromatinCRISPR-Cas SystemsDNA-Binding ProteinsDrosophila melanogasterGene EditingInsulator ElementsMicrotubule-Associated ProteinsNuclear ProteinsProtein BindingRepressor ProteinsChromatinCP190 protein, DrosophilaDNA-Binding ProteinsDrosophila ProteinsMicrotubule-Associated ProteinsNuclear ProteinsRepressor Proteinssu(Hw) protein, Drosophilaarchitectural C2H2 proteinsCP190enhancer–promoter communicationinsulatorlong-distance interactionsMod(mdg4)Su(Hw)

Identifiers

PMID38731837
PMCPMC11083095

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.