Evidence map›Paper›PMID 38731997›Full record

ArticleInternational journal of molecular sciences2024

Fetal Hypoglycemia Induced by Placental

Victoria C Kennedy, Cameron S Lynch, Amelia R Tanner, Quinton A Winger, Ahmed Gad, Paul J Rozance, Russell V Anthony

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Victoria C KennedyCollege of Veterinary Medicine, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0002-9303-3607
Cameron S LynchCollege of Veterinary Medicine, Colorado State University, Fort Collins, CO 80523, USA.
Amelia R TannerCollege of Veterinary Medicine, Colorado State University, Fort Collins, CO 80523, USA.
Quinton A WingerCollege of Veterinary Medicine, Colorado State University, Fort Collins, CO 80523, USA.
Ahmed GadCollege of Veterinary Medicine, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0001-9741-2105
Paul J RozanceUniversity of Colorado School of Medicine, Aurora, CO 80045, USA.
Russell V AnthonyCollege of Veterinary Medicine, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0003-3929-626X

Funding

Fetal glucagon links fetal metabolism with uterine blood flow and placental nutrient transfer by inhibiting placental lactogen secretionR01HD111557 · UNIVERSITY OF COLORADO DENVER · 2025 to 2025
$626k
National Institute of Health HD093701National Institute of Health HD094952National Institute of Health HD111557NICHD NIH HHS R01 HD093701NICHD NIH HHS R01 HD111557NICHD NIH HHS R21 HD094952United States Department of Agriculture 2021-67034-34969
6 · The paper itself

Abstract

Glucose, the primary energy substrate for fetal oxidative processes and growth, is transferred from maternal to fetal circulation down a concentration gradient by placental facilitative glucose transporters. In sheep, SLC2A1 and SLC2A3 are the primary transporters available in the placental epithelium, with SLC2A3 located on the maternal-facing apical trophoblast membrane and SLC2A1 located on the fetal-facing basolateral trophoblast membrane. We have previously reported that impaired placental SLC2A3 glucose transport resulted in smaller, hypoglycemic fetuses with reduced umbilical artery insulin and glucagon concentrations, in addition to diminished pancreas weights. These findings led us to subject RNA derived from

Indexed as

HypoglycemiaPancreasPlacentaRNA InterferenceTranscriptomeAnimalsFemaleFetal DevelopmentFetusGene Expression ProfilingGene Expression Regulation, DevelopmentalGlucoseGlucose Transporter Type 3PregnancySheepGlucoseGlucose Transporter Type 3glucagonglucose uptakeinsulinplacentaSLC2A3transcriptomics

Identifiers

PMID38731997
PMCPMC11084495

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.