ArticleJournal of medicinal chemistry2024
Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
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Article in Journal of medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8citing papers in PubMed
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Who cites it
8 citing papers in PubMed.
- Newly synthesized histones: passive or active players in the regulation of epigenetic inheritance?Nucleic acids research · 2026Review
- Cryo-EM Structure of Human ATAD2B Reveals a Hexameric Organization Contributes to ATPase Activity and Substrate Coordination.bioRxiv : the preprint server for biology · 2026Article
- Unraveling the complexity of the histone code: implications for gene regulation and disease.Genome biology · 2026Review
- Recent Progress and Prospect in Studying Selective Inhibitors Toward Bromodomain Family Members.Molecules (Basel, Switzerland) · 2026Review
- Breaking barriers: transitioning from X-ray crystallography to cryo-EM for structural studies.Acta crystallographica. Section D, Structural biology · 2026Article
- Breaking Barriers: Transitioning from X-ray Crystallography to Cryo-EM for Structural Studies of ATAD2B.bioRxiv : the preprint server for biology · 2025Article
- YEATS2 promotes malignant phenotypes of esophageal squamous cell carcinoma via H3K27ac activated-IL6ST.Frontiers in cell and developmental biology · 2025Article
- The CECR2 bromodomain displays distinct binding modes to select for acetylated histone proteins versus non-histone ligands.bioRxiv : the preprint server for biology · 2024Article
Corrections and comments
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Authors and funding
14 authors.
Margaret PhillipsDepartment of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, Vermont 05405, United States.
Kiera L MaloneDepartment of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, Vermont 05405, United States.
Brian W BoyleDepartment of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, Vermont 05405, United States.
Cameron MontgomeryDepartment of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, Vermont 05446, United States.
Isabelle A KressyDepartment of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, Vermont 05405, United States.
Faith M JosephVerna & Marrs McLean Department of Biochemistry & Molecular Pharmacology, Baylor College of Medicine, Houston, Texas 77030, United States.
Kathleen M BrightDepartment of Biomedical and Health Sciences, University of Vermont, Burlington, Vermont 05405, United States.
Samuel P BoysonDepartment of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, Vermont 05446, United States.
Sunsik ChangDepartment of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, Vermont 05446, United States.
Jay C NixMolecular Biology Consortium, Advanced Light Source, Berkeley, California 94720, United States.
Nicolas L YoungVerna & Marrs McLean Department of Biochemistry & Molecular Pharmacology, Baylor College of Medicine, Houston, Texas 77030, United States.ORCID 0000-0002-3323-2815
Victoria JeffersDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, New Hampshire 03824, United States.ORCID 0000-0003-1233-1088
Seth FrietzeDepartment of Biomedical and Health Sciences, University of Vermont, Burlington, Vermont 05405, United States.
Karen C GlassDepartment of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, Vermont 05405, United States.ORCID 0000-0002-2761-733X
Funding
User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI Gregory L Hura · 2017 to 2026
$28.6MTLR-TRIF mediated induction of GLI3 modulates innate inflammatory responsesP20GM113131 · NIGMS · UNIVERSITY OF NEW HAMPSHIRE · PI Sean Stoddart Coleman Edington · 2017 to 2026
$22.8MTMEM106b as a lysosomal adaptor to influence brain aging and tau pathogenesisP01AG066606 · NIA · BAYLOR COLLEGE OF MEDICINE · PI ZHENG, HUI · 2021 to 2025
$13.5MWATER DISTRIB:PHYSICAL PROPERT:PIZZA &LMPS MOZZARELLA CHEESES:EARLY STAGE MATURP41RR002301 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN LUTE · 1985 to 2011
$13.0MInitiative for Maximizing Student Development (IMSD) ProgramR25GM056929 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI PEREIRA, FRED A · 1998 to 2023
$12.4MTR&D 3: TECHNOLOGY DEVELOPMENT FOR NMR STUDIES OF SMALL MOLECULES (METABOLOMICS, NATURAL PRODUCTS, METABOLITE-PROTEIN INTERACTIONS) pp.537-585 P41GM103399 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BUTCHER, SAMUEL E · 2012 to 2019
$9.4MProject 3: MANCR Mediates Epigenetic Mechanisms for Survival of Advanced Breast CancerP01CA240685 · NCI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI STEIN, JANET L · 2021 to 2025
$8.7MNMR User Program at NMRFAMR24GM141526 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine Anne Henzler-Wildman · 2021 to 2026
$6.4MMETABOLIC REGULATION IN LEUKEMIA-INITIATING CELLSR01CA193235 · NCI · BAYLOR COLLEGE OF MEDICINE · PI NAKADA, DAISUKE · 2015 to 2024
$4.6MNeutron encoded activity based probesR01GM139295 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI YOUNG, DAMIAN WINSTON, YOUNG, NICOLAS L · 2020 to 2024
$2.2MDeciphering the molecular mechanisms of histone code recognition by ATAD2/BR01GM129338 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI FRIETZE, SETH E, GLASS, KAREN CHAMPAGNE · 2018 to 2022
$2.1MDevelopmental control of chromatin states in cancerR01CA276663 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian J Davis · 2023 to 2026
$1.7MNCI NIH HHS P01 CA240685NCI NIH HHS R01 CA193235NCI NIH HHS R01 CA276663NCRR NIH HHS P41 RR002301NHGRI NIH HHS R56 HG012206NIA NIH HHS P01 AG066606NIA NIH HHS R01 AG074540NIA NIH HHS RF1 AG074540NIGMS NIH HHS P20 GM113131NIGMS NIH HHS P30 GM124169NIGMS NIH HHS P41 GM103399NIGMS NIH HHS R01 GM129338NIGMS NIH HHS R01 GM139295NIGMS NIH HHS R15 GM104865NIGMS NIH HHS R24 GM141526NIGMS NIH HHS R25 GM056929NIGMS NIH HHS T32 GM152777
Abstract
The ATPase family AAA
Indexed as
ATPases Associated with Diverse Cellular ActivitiesDNA-Binding ProteinsHistonesLysineAcetylationAdenosine TriphosphatasesBinding SitesHumansModels, MolecularProtein BindingProtein DomainsProtein Processing, Post-TranslationalAdenosine TriphosphatasesATAD2 protein, humanATPases Associated with Diverse Cellular ActivitiesDNA-Binding ProteinsHistonesLysine
Identifiers
What Socratic holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.