Evidence mapPaperPMID 38734613Full record

ArticleBMC nephrology2024

Peritoneal dialysis related peritonitis: insights from a long-term analysis of an Italian center.

Luca Nardelli, Antonio Scalamogna, Federico Ponzano, Anna Sikharulidze, Federica Tripodi, Simone Vettoretti, Carlo Alfieri, Giuseppe Castellano

Abstract read
In one paragraph

Article in BMC nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luca NardelliDivision of Nephrology, Dialysis and Kidney Transplantation, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico 1, Via della Commenda 15, Milano, 20122, Italia. lcn.nardelli@gmail.com.
Antonio ScalamognaDivision of Nephrology, Dialysis and Kidney Transplantation, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico 1, Via della Commenda 15, Milano, 20122, Italia.
Federico PonzanoDivision of Nephrology, Dialysis and Kidney Transplantation, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico 1, Via della Commenda 15, Milano, 20122, Italia.
Anna SikharulidzeDivision of Nephrology, Dialysis and Kidney Transplantation, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico 1, Via della Commenda 15, Milano, 20122, Italia.
Federica TripodiDivision of Nephrology, Dialysis and Kidney Transplantation, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico 1, Via della Commenda 15, Milano, 20122, Italia.
Simone VettorettiDivision of Nephrology, Dialysis and Kidney Transplantation, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico 1, Via della Commenda 15, Milano, 20122, Italia.
Carlo AlfieriDivision of Nephrology, Dialysis and Kidney Transplantation, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico 1, Via della Commenda 15, Milano, 20122, Italia.
Giuseppe CastellanoDivision of Nephrology, Dialysis and Kidney Transplantation, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico 1, Via della Commenda 15, Milano, 20122, Italia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeritonitis is a common and severe complication of peritoneal dialysis (PD). For comparative analysis standardized definitions as well as measurements and outcomes are crucial. However, most PD-related peritonitis studies have been using heterogenous definitions and variable methods to measure outcomes. The ISPD 2022 guidelines have revised and clarified numerous definitions and proposed new peritonitis categories and outcomes.

methodsBetween 1st January 2009 and 31st May 2023, 267 patients who started PD at our institution were included in the study. All PD-related peritonitis episodes that occurred in our unit during the study period were collected. The new definitions and outcomes of ISPD 2022 recommendations were employed.

resultsThe overall peritonitis rate was 0.25 episode/patient year. Patient cumulative probability of remaining peritonitis-free at one year was 84.2%. The medical cure and refractory peritonitis rates were equal to 70.3 and 22.4%, respectively. Culture-negative peritonitis accounted for 25.6% of all specimens. The rates of peritonitis associated death, hemodialysis transfer, catheter removal and hospitalization were 6.8%, 18.3%, 18.7% and 64.4%, respectively. Relapsing, repeat, recurrent and enteric peritonitis accounted for 7.8%, 6.8%, 4.1% and 2.7% of all episodes, respectively. Catheter insertion, catheter related and pre-PD peritonitis were 4.2, 2.1 and 0.5%.

conclusionsThe implementation of PD-related peritonitis reports using standardized definitions and outcome measurements is of paramount importance to enhance clinical practice and to allow comparative studies.

Indexed as

Peritoneal DialysisPeritonitisAdultAgedFemaleHospitalizationHumansItalyKidney Failure, ChronicMaleMiddle AgedRetrospective StudiesCatheterHD transferHospitalizationMortalityPeritoneal dialysisPeritonitis

Identifiers

PMID38734613
PMCPMC11088076

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.