Evidence map›Paper›PMID 38736547›Full record

ReviewiScience2024

Vesicle fusion and release in neurons under dynamic mechanical equilibrium.

Wenhao Liu, Tianyu Gao, Na Li, Shuai Shao, Bo Liu

Abstract readReview
In one paragraph

Review in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenhao LiuCancer Hospital of Dalian University of Technology, Shenyang 110042, China.
Tianyu GaoCancer Hospital of Dalian University of Technology, Shenyang 110042, China.
Na LiCancer Hospital of Dalian University of Technology, Shenyang 110042, China.
Shuai ShaoCancer Hospital of Dalian University of Technology, Shenyang 110042, China.
Bo LiuCancer Hospital of Dalian University of Technology, Shenyang 110042, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vesicular fusion plays a pivotal role in cellular processes, involving stages like vesicle trafficking, fusion pore formation, content release, and membrane integration or separation. This dynamic process is regulated by a complex interplay of protein assemblies, osmotic forces, and membrane tension, which together maintain a mechanical equilibrium within the cell. Changes in cellular mechanics or external pressures prompt adjustments in this equilibrium, highlighting the system's adaptability. This review delves into the synergy between intracellular proteins, structural components, and external forces in facilitating vesicular fusion and release. It also explores how cells respond to mechanical stress, maintaining equilibrium and offering insights into vesicle fusion mechanisms and the development of neurological disorders.

Indexed as

BiophysicsNeuroscience

Identifiers

PMID38736547
PMCPMC11088343

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.