Evidence map›Paper›PMID 38738342›Full record

ReviewHistology and histopathology2025

Retinal ischemic diseases and promising therapeutic molecular targets.

Deokho Lee, Yohei Tomita, Kazuno Negishi, Toshihide Kurihara

Abstract readReview
PubMed Publisher
In one paragraph

Review in Histology and histopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Deokho Lee *Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.
Yohei Tomita *Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.
Kazuno NegishiDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Toshihide KuriharaLaboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.

Funding

Grants-in-Aid for Scientific Research. KAKENHI 15 K10881Grants-in-Aid for Scientific Research. KAKENHI 18 K09424JST SPRING JPMJSP2123
6 · The paper itself

Abstract

Retinal ischemia is a fundamental pathologic condition associated with retinal vascular occlusion, glaucoma, diabetic retinopathy, age-related macular degeneration, and other eye diseases. Extensive inflammation, redox imbalance, apoptosis, and abnormal vascular formation in retinal ischemia could lead to visual impairments. Developing or finding effective treatments is urgently needed to protect the eye against retinal ischemia and related damage. To address the demand, we have searched for promising therapeutic molecular targets in the eye (e.g., hypoxia-inducible factor [HIF], peroxisome proliferator-activated receptor-alpha [PPARα], and nicotinamide adenine dinucleotide [NAD

Indexed as

IschemiaRetinal DiseasesAnimalsHumansMolecular Targeted TherapyNADPPAR alphaRetinal VesselsNADPPAR alpha

Identifiers

PMID38738342

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.