Who was studied, and how
Two numbers in the abstract
Where each one falls
Where it lands on the map
What it changes
Among 23 other studies
1,145people with heart failure, in this paper
Among no diuretics, the trial randomly assignedassigned by chance
semaglutide
placebo
May have lowered body weight−8.80
randomised · one subgroup, may be chanceAmong highest loop diuretic dose category, the trial randomly assignedassigned by chance
semaglutide
placebo
May have lowered body weight−6.90
randomised · one subgroup, may be chancethe abstract, start to end
… mean difference vs. placebo ranged from -8.8% [95% confidence interval (CI) -10.3, -6.3] to -6.9% [95% CI -9.1, -4.7] from no …
← favours treatmentfavours comparator →
could be chanceChange in body weightsemaglutide vs placebo, in no diuretics
−8.8−10.3 to −6.30
Change in body weightsemaglutide vs placebo, in highest loop diuretic dose category
−6.9−9.10 to −4.70
GLP-1 receptor agonistsBody weight & composition
GLP-1 receptor agonists × body weight & compositionhelps?replicated
unlikelylikely
0.900.90 without it
← favours treatmentfavours comparator →
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