Evidence map›Paper›PMID 38739296›Full record

ArticleActa diabetologica2024

The interplay between excess weight and hyper-glycemia on NCDs in Italy: results from a cross-sectional study.

Vincenzo Atella, Federico Belotti, Matilde Giaccherini, Gerardo Medea, Andrea Piano Mortari, Paolo Sbraccia, Antonio Nicolucci

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Article in Acta diabetologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

  1. Observational
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Vincenzo AtellaDepartment of Economics and Finance, University of Rome Tor Vergata, Rome, Italy.
Federico BelottiDepartment of Economics and Finance, University of Rome Tor Vergata, Rome, Italy.
Matilde GiaccheriniCEIS Tor Vergata, University of Rome Tor Vergata, Rome, Italy.
Gerardo MedeaItalian College of General Practitioners, Florence, Italy.
Andrea Piano MortariCEIS Tor Vergata, University of Rome Tor Vergata, Rome, Italy.
Paolo SbracciaDepartment of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Antonio NicolucciCenter for Outcomes Research and Clinical Epidemiology-CORESEARCH, Corso Umberto I, 103, 65122, Pescara, Italy. nicolucci@coresearch.it.ORCID http://orcid.org/0000-0002-5939-6850

Funding

Novo Nordisk analysisNovo Nordisk collectionNovo Nordisk conduct of the studyNovo Nordisk interpretation of the data; or the preparationNovo Nordisk managementNovo Nordisk review of the manuscript.Novo Nordisk This work was supported by NovoNordisk Italy which had no role in the study design
6 · The paper itself

Abstract

purposeTo evaluate the prevalence of chronic comorbidities according to BMI classes and assess the interplay between excess body weight and blood glucose abnormalities in increasing the risk of major chronic diseases.

methodsThe study is based on data from the Health Search/IQVIA Health LPD Longitudinal Patient Database, an Italian general practice registry, with data obtained from electronic clinical records of 800 general practitioners throughout Italy. Data relative to the year 2018 were analyzed. The study population was classified according to BMI (normal weight, overweight, and obesity classes 1, 2 and 3) and glucose metabolism status (normoglycemia-NGT; impaired fasting glucose-IFG; diabetes mellitus-DM). Comorbidities were identified through ICD-9 CM codes.

resultsData relative to 991,917 adults were analyzed. The prevalence of overweight was 39.4%, while the prevalence of obesity was 11.1% (class 1: 7.9%, class 2: 2.3%, class 3: 0.9%). In the whole population, the prevalence of DM and IFG was 8.9% and 4.2%, respectively. Both overweight and obesity were associated with an increasing prevalence of glucose metabolism alterations and a large array of different chronic conditions, including cardio-cerebrovascular diseases, heart failure, chronic kidney disease, osteoarticular diseases, depression, sleep apnea, and neoplasms of the gastrointestinal tract. Within each BMI class, the presence of IFG, and to a greater extent DM, identified subgroups of individuals with a marked increase in the risk of concomitant chronic conditions.

conclusionAddressing the double burden of excess weight and hyperglycemia represents an important challenge and a healthcare priority.

Indexed as

OverweightAdultAgedBlood GlucoseBody Mass IndexComorbidityCross-Sectional StudiesFemaleHumansHyperglycemiaItalyMaleMiddle AgedNoncommunicable DiseasesObesityPrevalenceBlood GlucoseClinical burdenComorbiditiesEpidemiologyGlucose metabolism alterationsObesityOverweight

Identifiers

PMID38739296
PMCPMC11379753

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