Evidence map›Paper›PMID 38739880›Full record

Trial reportNeurology2024

Effect of Endovascular Thrombectomy for Acute Ischemic Stroke on Cognitive Outcomes: A Secondary Analysis of the ESCAPE Trial.

Raed A Joundi, Eric E Smith, Jennifer Mandzia, Aravind Ganesh, Bijoy K Menon, Jeremy L Rempel, John Thornton, Daniel Roy, Tudor G Jovin, Dar Dowlatshahi and 23 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Vascular cognitive impairment and dementia: Mechanisms, treatment, and future directions.International journal of stroke : official journal of the International Stroke Society · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Raed A JoundiFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0001-9554-0701
Eric E SmithFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0003-3956-1668
Jennifer MandziaFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0002-1331-0695
Aravind GaneshFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Bijoy K MenonFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Jeremy L RempelFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
John ThorntonFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Daniel RoyFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0002-6066-4453
Tudor G JovinFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0002-2619-6975
Dar DowlatshahiFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0003-1379-3612
Donald F FreiFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Aditya BharathaFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Alexandre PoppeFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Frank L SilverFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Ashfaq ShuaibFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Jeanne S TeitelbaumFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
David WilliamsFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0002-1923-462X
Oh Young BangFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Biggya L SapkotaFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Paul BurnsFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Hana ChoeFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Jie-Hoe HeoFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Michael E KellyFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Guillermo LinaresFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Jai J ShankarFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.
Sung-Il SohnFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0002-6900-1242
Richard H SwartzFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0001-6571-5531
Philip BarberFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0002-6051-1078
Shelagh B CouttsFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0001-5090-5105
Andrew DemchukFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0002-4930-7789
Mayank GoyalFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0001-9060-2109
Michael D HillFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.ORCID 0000-0002-6269-1543
ESCAPE Trial InvestigatorsFrom the Division of Neurology (R.A.J.), Hamilton Health Sciences, McMaster University & Population Health Research Institute, Hamilton, Ontario; Department of Clinical Neurosciences (E.E.S., B.K.M., A.G., P. Barber, S.B.C., A.D., M.G., M.D.H.), Hotchkiss Brain Institute, Departments of Radiology (E.E.S., B.K.M., A.G., A.D., M.G., M.D.H.), and Medicine (M.D.H.), Cumming School of Medicine, and Department of Community Health Sciences (E.E.S., B.K.M., A.G., M.D.H.), University of Calgary, Alberta; Department of Clinical Neurological Sciences (J.M.), Western University and London Health Sciences Center, Ontario; Departments of Radiology (J.L.R.), and Medicine (Neurology) (A.S.), University of Alberta Hospital, Edmonton, Canada; Department of Radiology (J.T.), Beaumont Hospital, Dublin, Ireland; Department of Radiology (D.R.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec, Canada; Department of Neurology (T.G.J.), Cooper University Health Care, Camden, NJ; Department of Medicine (Neurology) (D.D.), University of Ottawa, Ottawa Hospital, Ontario, Canada; Radiology Imaging Associates (D.F.F.), Swedish Medical Centre, Englewood, CO; Division of Neurology (F.L.S.), Department of Medicine and Department of Radiology (A.B.), University of Toronto, St. Michael's Hospital, Ontario; Department of Neurosciences (A.P.), Université de Montréal, Centre Hospitalier de l'Université de Montréal (CHUM), Québec; Department of Neurology (J.S.T.), Montreal Neurological Institute, Québec, Canada; Department of Neurology (D.W.), Royal College of Surgeons Ireland, Beaumont Hospital, Dublin; Department of Neurology (O.Y.B.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Providence Neurological Specialties (B.L.S.), Providence Health Care, Portland, OR; Department of Neuroradiology (P. Burns), Royal Victoria Hospital, Belfast, United Kingdom; Department of Neuroradiology (H.C.), Community Regional Medical Centre, Fresno, CA; Department of Neurology (J.-H.H.), Severance Medical Centre, Yonsei University, Seoul, South Korea; Department of Surgery (Neurosurgery) (M.E.K.), University of Saskatoon, Royal Saskatoon Hospital, Saskatchewan, Canada; St. Louis University (G.L.), Souers Stroke Institute, MO; Department of Radiology (J.J.S.), University of Manitoba, Health Sciences Centre, Winnipeg, Canada; Department of Neurology (S.-I.S.), Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea; and Department of Medicine (Neurology) (R.H.S.), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe effect of endovascular therapy (EVT) for large vessel occlusion stroke on cognitive outcomes is not well understood. We evaluated the effect of EVT on cognitive function in the Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times (ESCAPE) trial.

methodsPatient data from the ESCAPE randomized trial were analyzed. Cognitive assessments completed at 90 days after stroke were the Montreal Cognitive Assessment (MoCA), the Sunnybrook Neglect Assessment Procedure (SNAP), the Boston Naming Test (BNT), Trail-making test A (Trails A), and Trail-making test B (Trails B). We used logistic regression to evaluate the association between EVT and favorable cognitive outcome on the 5 separate tests, adjusting for demographic and clinical factors. We used generalized estimating equations and ordinal regression to determine the odds of favorable outcome with EVT on global cognition incorporating the 5 tests. We added final infarct volume (FIV) to the models to assess the relationship of FIV with cognitive outcome.

resultsThe ESCAPE trial included 315 patients, 165 randomized to EVT and 150 randomized to control. There was higher odds of favorable outcome with EVT for MoCA (adjusted odds ratio [aOR] 2.32, 95% CI 1.30-4.16), SNAP (aOR 3.85, 95% CI 2.00-7.45), BNT (aOR 2.33, 95% CI 1.30-4.17), trails A (aOR 3.50, 95% CI 1.93-6.36), and trails B (aOR 2.56, 95% CI 1.46-4.48). There was higher odds of favorable outcome with EVT on global binary (aOR 2.57, 95% CI 1.67-3.94) and ordinal analyses (aOR 2.83, 95% CI 1.68-4.76) of cognitive function. After adding FIV to the models, both FIV and EVT were significantly associated with cognitive outcome. There was a significant correlation between global cognitive performance and mRS at day 90 ( DISCUSSION: In this secondary analysis of the ESCAPE trial, EVT was associated with favorable outcome on 5 separate cognitive tests and in global analyses of cognitive benefit. These results provide novel evidence for the effect of EVT on cognition and support the global benefit of treatment with EVT. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that in patients with acute ischemic stroke due to intracranial internal carotid artery (ICA) or M1 segment MCA occlusion, including tandem extracranial ICA occlusions, EVT compared with best medical therapy increased odds of favorable cognitive outcome.

Indexed as

Endovascular ProceduresIschemic StrokeThrombectomyAgedAged, 80 and overCognitionFemaleHumansMaleMiddle AgedNeuropsychological TestsTreatment Outcome

Identifiers

PMID38739880
PMCPMC11177593

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.