Evidence map›Paper›PMID 38746235›Full record

ArticlebioRxiv : the preprint server for biology2024

Multiple inositol phosphate species enhance stability of active mTOR.

Lucia E Rameh, John D York, Raymond D Blind

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lucia E RamehUniversity of South Alabama, Department of Biochemistry and Molecular Biology, Mobile, AL 36688.ORCID 0000-0003-4257-542X
John D YorkVanderbilt University School of Medicine, Department of Biochemistry, Nashville, TN 37232.ORCID 0000-0002-3270-6345
Raymond D BlindVanderbilt University School of Medicine, Department of Biochemistry, Nashville, TN 37232.ORCID 0000-0002-1358-6309

Funding

Inositol hexakisphosphate regulation of N-terminal acetyltransferasesR01GM124404 · NIGMS · VANDERBILT UNIVERSITY · PI YORK, JOHN D. · 2017 to 2020
$1.6M
IPMK function in chromatinR01GM132592 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLIND, RAYMOND DANIEL · 2020 to 2023
$1.5M
Unconventional regulation of mTORC1 signaling by inositol phosphate: implications for nutrient-induced premature agingR21AG071975 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLIND, RAYMOND DANIEL, BURKEWITZ, KRISTOPHER · 2022 to 2023
$483k
NIA NIH HHS R21 AG071975NIGMS NIH HHS R01 GM124404NIGMS NIH HHS R01 GM132592
6 · The paper itself

Abstract

Mechanistic Target of Rapamycin (mTOR) binds the small metabolite inositol hexakisphosphate (IP

Identifiers

PMID38746235
PMCPMC11092565

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.