Evidence mapPaperPMID 38747752Full record

ArticleBrain and behavior2024

White matter hyperintensity, parent artery steno-occlusion, and neurological deterioration in anterior circulation single subcortical infarction patients.

Yunhe Luo, Daosheng Wang, Yiming Jia, Xin Gu, Yuhan Zang, Zhengbao Zhu, Jin Zheng, Ligang Huang, Jing Zhao

Abstract read
In one paragraph

Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yunhe LuoDepartment of Neurology, Minhang Hospital, Fudan University, Shanghai, China.
Daosheng WangDepartment of Neurosurgery, Minhang Hospital, Fudan University, Shanghai, China.
Yiming JiaDepartment of Epidemiology, School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, China.
Xin GuDepartment of Neurology, Minhang Hospital, Fudan University, Shanghai, China.
Yuhan ZangDepartment of Epidemiology, School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, China.
Zhengbao ZhuDepartment of Epidemiology, School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, China.
Jin ZhengDepartment of Neurology, Minhang Hospital, Fudan University, Shanghai, China.
Ligang HuangDepartment of Neurology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Jing ZhaoDepartment of Neurology, Minhang Hospital, Fudan University, Shanghai, China.ORCID 0000-0001-5197-9181

Funding

National Natural Science Foundation of China 81973157National Natural Science Foundation of China 82173646Shanghai Minhang Science and Technology Commission 2019MHZ081
6 · The paper itself

Abstract

backgroundThe evidence for the association between white matter hyperintensity (WMH) severity and neurological deterioration (ND) in patients with single subcortical infarction (SSI) remains unclear and whether the association between them is modified by anterior circulation parent artery steno-occlusion (PAS) is unknown. Herein, we aimed to prospectively investigate the internal relevance.

methodsIn this prospective study, the severity of WMH and PAS were assessed in 288 consecutive patients with anterior circulation SSI arriving at our hospital, a tertiary teaching hospital affiliated with Fudan University, 24 h after onset from January 2017 to December 2018. The multivariable logistic regression model was used to estimate the association between WMH severity and the risk of ND within 7 days after stroke onset as well as the interactive effect between WMH severity and PAS on ND among patients with SSI.

resultsPAS modified the association between WMH severity and ND among patients with SSI (p

conclusionThere was a modified effect of PAS on the association between WMH severity and ND within 7 days after stroke onset among patients with anterior circulation SSI, which deserves more research attention. WMH was negatively associated with ND in anterior circulation SSI patients without PAS.

Indexed as

White MatterAgedCerebral InfarctionFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesSeverity of Illness Indexacute ischemic strokeneurological deteriorationparent artery steno‐occlusionsingle subcortical infarctionwhite matter hyperintensity

Identifiers

PMID38747752
PMCPMC11095297

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.