Evidence map›Paper›PMID 38748376›Full record

SynthesisJournal of epidemiology and global health2024

Attack Rate, Case Fatality Rate and Predictors of Pertussis Outbreak During Pertussis Outbreak Investigation in Ethiopia: Systematic Review and Meta-Analysis.

Mengistie Kassahun Tariku, Abebe Habtamu Belete, Daniel Tarekegn Worede, Simachew Animen Bante, Agumas Alemu Alehegn, Biniam Kebede Assen, Bantayehu Addis Tegegne, Sewnet Wongiel Misikir

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of epidemiology and global health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mengistie Kassahun TarikuDepartment of Public Health, College of Health Science, Debre Markos University, Debre Markos, Ethiopia. mengesh2009@gmail.com.
Abebe Habtamu BeleteDepartment of Public Health, College of Health Science, Debre Markos University, Debre Markos, Ethiopia.
Daniel Tarekegn WoredeDepartment of Public Health, College of Health Science, Debre Markos University, Debre Markos, Ethiopia.
Simachew Animen BanteDepartment of Midwifery, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.
Agumas Alemu AlehegnAmhara Regional State Public Health Institute, Bahir Dar, Ethiopia.
Biniam Kebede AssenAmhara Regional State Public Health Institute, Bahir Dar, Ethiopia.
Bantayehu Addis TegegneDepartment of Pharmacy, College of Health Science, Debre Markos University, Debre Markos, Ethiopia.
Sewnet Wongiel MisikirDepartment of Medical Laboratory Technology, Felege Hiwot Comprehensive Specialized Hospital, Bahir Dar, 680, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPertussis, a highly contagious, vaccine-preventable respiratory infection caused by Bordetella pertussis, is a leading global public health issue. Ethiopia is currently conducting multiple pertussis outbreak investigations, but there is a lack of comprehensive information on attack rate, case fatality rate, and infection predictors. This study aimed to measure attack rates, case fatality rates, and factors associated with pertussis outbreak.

methodsThis study conducted a systematic review and meta-analysis of published and unpublished studies on pertussis outbreaks in Ethiopia from 2009 to 2023, using observational study designs, using the guideline Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The study utilized databases like Science Direct, MEDLINE/PubMed, African Journals Online, Google Scholar and registers. The data were collected using an Excel Spreadsheet and then exported to STATA version 17 for analysis. Subgroup analysis was conducted to identify potential disparities. A random effects model was used to consider heterogeneity among studies. I

resultsSeven pertussis outbreak investigations with a total of 2824 cases and 18 deaths were incorporated. The pooled attack and case fatality rates were 10.78 (95% CI: 8.1-13.5) per 1000 population and 0.8% (95% CI: 0.01-1.58%), respectively. The highest and lowest attack rates were in Oromia (5.57 per 1000 population and in the Amhara region (2.61 per 1000 population), respectively. Predictor of pertussis outbreak were being unvaccinated [odds ratio (OR) = 3.05, 95% CI: 1.83-4.27] and contact history [OR = 3.44, 95% CI: 1.69-5.19].

conclusionHigher and notable variations in attack and case fatality rates were reported. Being unvaccinated and having contact history were the predictors of contracting pertussis disease in Ethiopia. Enhancing routine vaccination and contact tracing efforts should be strengthened.

Indexed as

Disease OutbreaksWhooping CoughEthiopiaHumansIncidenceEthiopiaOutbreakPertussisReview

Identifiers

PMID38748376
PMCPMC11176133

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.