Evidence map›Paper›PMID 38750280›Full record

ArticleMedical & biological engineering & computing2024

The ECG abnormalities in persons with chronic disorders of consciousness.

Xiaodan Tan, Minmin Luo, Qiuyi Xiao, Xiaochun Zheng, Jiajia Kang, Daogang Zha, Qiuyou Xie, Chang'an A Zhan

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Article in Medical & biological engineering & computing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Xiaodan TanSchool of Biomedical Engineering, Southern Medical University, No. 1023, Shatainan Road, Baiyun District, Guangzhou, 510515, Guangdong Province, China.
Minmin LuoSchool of Biomedical Engineering, Southern Medical University, No. 1023, Shatainan Road, Baiyun District, Guangzhou, 510515, Guangdong Province, China.
Qiuyi XiaoJoint Research Centre for Disorders of Consciousness, Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Avenue Central, Guangzhou, 510280, Guangdong Province, China.
Xiaochun ZhengJoint Research Centre for Disorders of Consciousness, Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Avenue Central, Guangzhou, 510280, Guangdong Province, China.
Jiajia KangSchool of Biomedical Engineering, Southern Medical University, No. 1023, Shatainan Road, Baiyun District, Guangzhou, 510515, Guangdong Province, China.
Daogang ZhaDepartment of General Practice, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qiuyou XieJoint Research Centre for Disorders of Consciousness, Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Avenue Central, Guangzhou, 510280, Guangdong Province, China. xqy7180@163.com.ORCID http://orcid.org/0000-0002-8333-0165
Chang'an A ZhanSchool of Biomedical Engineering, Southern Medical University, No. 1023, Shatainan Road, Baiyun District, Guangzhou, 510515, Guangdong Province, China. cznelab@smu.edu.cn.ORCID http://orcid.org/0000-0001-8017-1886

Funding

National Natural Science Foundation of China 81974154National Natural Science Foundation of China 82371184Natural Science Foundation of Guangdong Province 2023A1515011843
6 · The paper itself

Abstract

We aimed to investigate the electrocardiogram (ECG) features in persons with chronic disorders of consciousness (DOC, ≥ 29 days since injury, DSI) resulted from the most severe brain damages. The ECG data from 30 patients with chronic DOC and 18 healthy controls (HCs) were recorded during resting wakefulness state for about five minutes. The patients were classified into vegetative state (VS) and minimally conscious state (MCS). Eight ECG metrics were extracted for comparisons between the subject subgroups, and regression analysis of the metrics were conducted on the DSI (29-593 days). The DOC patients exhibit a significantly higher heart rate (HR, p = 0.009) and lower values for SDNN (p = 0.001), CVRR (p = 0.009), and T-wave amplitude (p < 0.001) compared to the HCs. However, there're no significant differences in QRS, QT, QTc, or ST amplitude between the two groups (p > 0.05). Three ECG metrics of the DOC patients-HR, SDNN, and CVRR-are significantly correlated with the DSI. The ECG abnormalities persist in chronic DOC patients. The abnormalities are mainly manifested in the rhythm features HR, SDNN and CVRR, but not the waveform features such as QRS width, QT, QTc, ST and T-wave amplitudes.

Indexed as

Consciousness DisordersElectrocardiographyHeart RateAdultCase-Control StudiesChronic DiseaseFemaleHumansMaleMiddle AgedPersistent Vegetative StateAutonomic functionDisorders of consciousnessECG abnormalitiesNeurorehabilitation

Identifiers

PMID38750280

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.