Evidence map›Paper›PMID 38751794›Full record

ArticleKidney diseases (Basel, Switzerland)2024

Association of Serum Unsaturated Fatty Acid Patterns with the Risk of Diabetic Nephropathy.

Shuang Xu, Xinyuan Li, Qing Hou, Ning Xu, Qingmiao Lu, Sudan Wang, Chunsun Dai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Kidney diseases (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuang XuCenter for Kidney Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xinyuan LiCenter for Kidney Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qing HouCenter for Kidney Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ning XuCenter for Kidney Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qingmiao LuCenter for Kidney Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Sudan WangCenter for Kidney Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Chunsun DaiCenter for Kidney Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Unsaturated fatty acids play an essential role in the progression of diabetic nephropathy (DN). However, previous studies were mainly focused on the role of individual unsaturated fatty acid. The serum unsaturated fatty acid patterns (FAPs) in patients with DN remain to be determined. Methods: A total of 135 patients with DN (DN group) and 322 patients with type II diabetes without nephropathy (non-DN group) were included in this study. Clinical data, serum levels of unsaturated fatty acids, and other laboratory indicators were collected. Multivariate logistic regression was applied to identify risk factors for serum unsaturated fatty acid level in both groups. Serum unsaturated fatty acids were subjected to factor analysis to identify distinct FAPs. Multivariable logistic regression was employed to assess the risk of DN associated with different serum FAPs. Results: After adjusting for confounders, three types of unsaturated fatty acid including C20:5 (eicosapentaenoic acid [EPA]), C22:6 (docosahexaenoic acid [DHA]), and C22:5 Conclusions: Our findings suggest that FAP2 which is enriched with DHA and EPA is associated with a reduced risk of DN. This highlights the potential of targeting FAP2 for the patients with DN.

Indexed as

Diabetic nephropathyFactor analysisOmega-3 fatty acidsOmega-6 fatty acidsSerum unsaturated fatty acid patterns

Identifiers

PMID38751794
PMCPMC11095590

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.