Evidence map›Paper›PMID 38753277›Full record

ArticleChinese journal of integrative medicine2024

Treg Immunomodulation Contributes to the Anti-atherosclerotic Effects of Huxin Formula in ApoE

Xiao-Min Ou, Jing Cai, Xiao-Yue Hu, Qiao-Huang Zeng, Tao-Hua Lan, Wei Jiang

Abstract read
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In one paragraph

Article in Chinese journal of integrative medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiao-Min OuThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Jing CaiThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Xiao-Yue HuThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Qiao-Huang ZengDepartment of Cardiology, Guangdong Provincial Hospital of Chinese Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510020, China.
Tao-Hua LanDepartment of Cardiology, Guangdong Provincial Hospital of Chinese Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510020, China.
Wei JiangDepartment of Cardiology, Guangdong Provincial Hospital of Chinese Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510020, China. jiangwei@gzucm.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the effects of Huxin formula (HXF) in curtailing atherosclerosis and its underlying mechanism.

methodsAccording to random number table method, 24 specific pathogen free male ApoE

resultsHXF reduced plaque area in ApoE

conclusionHXF relieved atherosclerosis, probably by restraining inflammatory response, reducing inflammatory cell infiltration and attenuating aortic root fibrosis by increasing Treg counts.

Indexed as

Apolipoproteins EAtherosclerosisDrugs, Chinese HerbalImmunomodulationMice, Inbred C57BLT-Lymphocytes, RegulatoryAnimalsAortaCytokinesMaleMiceApolipoproteins ECytokinesDrugs, Chinese HerbalatherosclerosisHuxin Formulaimmune responsesinflammationTregs

Identifiers

PMID38753277

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.