Evidence map›Paper›PMID 38755627›Full record

ReviewNutrition & metabolism2024

Natural products in the management of neurodegenerative diseases.

Rajat Goyal, Pooja Mittal, Rupesh K Gautam, Mohammad Amjad Kamal, Asma Perveen, Vandana Garg, Athanasios Alexiou, Muhammad Saboor, Shafiul Haque, Aisha Farhana and 2 more

Abstract readReview
In one paragraph

Review in Nutrition & metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Synthetic Cyclic CAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  4. Review
  5. International journal of molecular sciences · 2026
    Article
  6. Mapping the Polar Neuro-Interactome ofLife (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Mechanistic Insights into the Neuroprotective Potential ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  16. Article
  17. Review
  18. Phytochemical Investigation ofPlants (Basel, Switzerland) · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rajat Goyal *MM College of Pharmacy, Maharishi Markandeshwar (Deemed to Be University), Mullana-Ambala, Haryana, 133207, India.
Pooja Mittal *Chitkara College of Pharmacy, Chitkara University, Rajpura-Punjab, India.
Rupesh K GautamDepartment of Pharmacology, Indore Institute of Pharmacy, IIST Campus, Rau, Indore, India. rupeshgautammmu@gmail.com.
Mohammad Amjad KamalInstitute for Systems Genetics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu,, China.
Asma PerveenGlocal School of Life Sciences, Glocal University, Uttar Pradesh, Saharanpur, India.
Vandana GargDepartment of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak Haryana, 124001, India.
Athanasios AlexiouUniversity Centre for Research & Development, Chandigarh University, Chandigarh-Ludhiana Highway, Mohali, Punjab, India.ORCID http://orcid.org/0000-0002-2206-7236
Muhammad SaboorDepartment of Medical Laboratory Sciences, University of Sharjah, College of Health Sciences, and Research Institute for Medical and Health Sciences, Sharjah, United Arab Emirates.
Shafiul HaqueResearch and Scientific Studies Unit, College of Nursing and Health Sciences, Jazan University, 45142, Jazan, Saudi Arabia.
Aisha FarhanaDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, 72388, Aljouf, Saudi Arabia.
Marios PapadakisDepartment of Surgery II, University Hospital Witten-Herdecke, University of Witten-Herdecke, Heusnerstrasse 40, 42283, Wuppertal, Germany. marios_papadakis@yahoo.gr.ORCID http://orcid.org/0000-0002-9020-874X
Ghulam Md AshrafDepartment of Medical Laboratory Sciences, University of Sharjah, College of Health Sciences, and Research Institute for Medical and Health Sciences, Sharjah, United Arab Emirates. ashraf.gm@gmail.com.

Funding

King Abdulaziz University KEP-36-130-42
6 · The paper itself

Abstract

Neurodegenerative diseases represent one of the utmost imperative well-being health issues and apprehensions due to their escalating incidence of mortality. Natural derivatives are more efficacious in various preclinical models of neurodegenerative illnesses. These natural compounds include phytoconstituents in herbs, vegetables, fruits, nuts, and marine and freshwater flora, with remarkable efficacy in mitigating neurodegeneration and enhancing cognitive abilities in preclinical models. According to the latest research, the therapeutic activity of natural substances can be increased by adding phytoconstituents in nanocarriers such as nanoparticles, nanogels, and nanostructured lipid carriers. They can enhance the stability and specificity of the bioactive compounds to a more considerable extent. Nanotechnology can also provide targeting, enhancing their specificity to the respective site of action. In light of these findings, this article discusses the biological and therapeutic potential of natural products and their bioactive derivatives to exert neuroprotective effects and some clinical studies assessing their translational potential to treat neurodegenerative disorders.

Indexed as

NanotechnologyNatural productsNeurodegenerative diseasesNeuroinflammationOxidative stress

Identifiers

PMID38755627
PMCPMC11100221

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.