Evidence map›Paper›PMID 38756071›Full record

ReviewPharmaceutical nanotechnology2025

Smart Multifunctional Nanoparticles in Cancer Theranostics: Progress and Prospect.

Dipanjan Karati, Swarupananda Mukherjee, Ayon Dutta, Dipanjana Ash, Shayeri Chatterjee Ganguly, Apurbaa Acharya, Biswajit Basu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pharmaceutical nanotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dipanjan KaratiDepartment of Pharmaceutical Technology, School of Pharmacy, Techno India University, Kolkata, 700091, West Bengal, India.
Swarupananda MukherjeeDepartment of Pharmaceutical Technology, NSHM Knowledge Campus, Kolkata, 700053, West Bengal, India.
Ayon DuttaDepartment of Pharmaceutical Technology, Brainware University, 398, Ramkrishnapur Road, Barasat, Kolkata, 700125, West Bengal, India.
Dipanjana AshDepartment of Pharmaceutical Technology, BCDA College of Pharmacy & Technology, 78/1, Jessore Road, Hridaypur (S), Barasat, Kolkata, 700127, West Bengal, India.
Shayeri Chatterjee GangulyDepartment of Pharmaceutical Technology, Brainware University, 398, Ramkrishnapur Road, Barasat, Kolkata, 700125, West Bengal, India.
Apurbaa AcharyaDepartment of Pharmaceutical Technology, Adamas University, Barasat - Barrackpore Road, Kolkata, 700126, West Bengal, India.
Biswajit BasuDepartment of Pharmaceutical Technology, Adamas University, Barasat - Barrackpore Road, Kolkata, 700126, West Bengal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWorldwide, cancer is the second most common cause of death. Chemotherapy and other traditional cancer treatments have toxicities that affect normal cells in addition to their intended targets, necessitating the development of novel approaches to enhance cell-specific targeting.

methodsThe present work summarizes the scientific information on nanoparticles in cancer theranostics to provide a comprehensive insight into the preventive and therapeutic potential of nanoparticles in cancer. Scopus, PubMed, Science Direct, and Google Scholar databases are searched to collect all the recent (2015-2023) scientific information on smart multifunctional nanoparticles using the terms nanotechnology, cancer theranostics, and polymer.

resultsThe use of nanomaterials as chemical biology tools in cancer theranostics has been thoroughly investigated. They demonstrate expanded uses in terms of stability, biocompatibility, and enhanced cell permeability, enabling precision targeting and ameliorating the drawbacks of conventional cancer treatments. The nano platform presents a fascinating chance to acquire multifunctionality and targeting techniques. The production of smart nanomaterials, specifically with regard to the advent of nanotechnology, has revolutionized the diagnosis and treatment of cancer. The capability of nanoparticles to functionalize with a variety of biosubstrates, including aptamers, antibodies, DNA, and RNA, and their broad surface area allow them to encapsulate a huge number of molecules, contributing to their theranostic effect. Comparatively speaking, economical, easily produced, and less toxic nanomaterials formed from biological sources are thought to have benefits over those made using conventional processes.

conclusionThe present study highlights the uses of several nanoparticles (NPs), and describes numerous cancer theranostics methodologies. The benefits and difficulties preventing their adoption in cancer treatment and diagnostic applications are also critically reviewed. The use of smart nanomaterials, according to this review's findings, can considerably advance cancer theranostics and open up new avenues for tumor detection and treatment.

Indexed as

Antineoplastic AgentsMultifunctional NanoparticlesNeoplasmsTheranostic NanomedicineAnimalsDrug Delivery SystemsHumansAntineoplastic Agentscancer theranosticsdrug delivery.nanomedicinenanoparticlesNanotechnologypolymer

Identifiers

PMID38756071

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.