Evidence map›Paper›PMID 38758367›Full record

ArticleClinical and experimental medicine2024

IFN-α/β/IFN-γ/IL-15 pathways identify GBP1-expressing tumors with an immune-responsive phenotype.

Lei Wang, Yuxuan Wei, Zheng Jin, Fangfang Liu, Xuchang Li, Xiao Zhang, Xiumei Bai, Qingzhu Jia, Bo Zhu, Qian Chu

Abstract read
In one paragraph

Article in Clinical and experimental medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lei Wang *Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China.
Yuxuan WeiDepartment of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China.
Zheng Jin *Institute of Life Sciences, Chongqing Medical University, Chongqing, 400032, People's Republic of China.
Fangfang LiuDepartment of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China.
Xuchang LiDepartment of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China.
Xiao ZhangArmy 953 Hospital, Shigatse Branch of Xinqiao Hospital, Army Medical University, Shigatse, 857000, People's Republic of China.
Xiumei BaiArmy 953 Hospital, Shigatse Branch of Xinqiao Hospital, Army Medical University, Shigatse, 857000, People's Republic of China.
Qingzhu JiaDepartment of Oncology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.
Bo ZhuDepartment of Oncology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, People's Republic of China.
Qian ChuDepartment of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China. qianchu@tjh.tjmu.edu.cn.

Funding

National Natural Science Foundation of China 62131009, 82072597National Natural Science Foundation of China 82073147
6 · The paper itself

Abstract

Immunotherapy is widely used in cancer treatment; however, only a subset of patients responds well to it. Significant efforts have been made to identify patients who will benefit from immunotherapy. Successful anti-tumor immunity depends on an intact cancer-immunity cycle, especially long-lasting CD8

Indexed as

GTP-Binding ProteinsImmunotherapyNeoplasmsCD8-Positive T-LymphocytesHumansInterferon-alphaInterferon-betaInterferon-gammaInterleukin-15Signal TransductionGBP1 protein, humanGTP-Binding ProteinsIL15 protein, humanInterferon-alphaInterferon-betaInterferon-gammaInterleukin-15BiomarkerGBP1ImmunotherapyTumor microenvironment

Identifiers

PMID38758367
PMCPMC11101573

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.