Evidence mapPaperPMID 38773261Full record

ArticleEye (London, England)2024

Colour fusion effect on deep learning classification of uveal melanoma.

Albert K Dadzie, Sabrina P Iddir, Mansour Abtahi, Behrouz Ebrahimi, David Le, Sanjay Ganesh, Taeyoon Son, Michael J Heiferman, Xincheng Yao

Abstract read
In one paragraph

Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Deep learning for early diagnosis of uveal melanoma: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Pooled it
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  8. Imaging-based machine learning for the diagnosis and prognosis of uveal melanoma: a systematic review and meta analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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  16. Automated segmentation for early detection of uveal melanoma.Canadian journal of ophthalmology. Journal canadien d'ophtalmologie · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Albert K DadzieDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL, 60607, USA.ORCID http://orcid.org/0000-0002-3466-5188
Sabrina P IddirDepartment of Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL, 60612, USA.
Mansour AbtahiDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL, 60607, USA.
Behrouz EbrahimiDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL, 60607, USA.
David LeDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL, 60607, USA.
Sanjay GaneshDepartment of Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL, 60612, USA.
Taeyoon SonDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL, 60607, USA.
Michael J HeifermanDepartment of Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL, 60612, USA. mheif@uic.edu.ORCID http://orcid.org/0000-0003-3456-0164
Xincheng YaoDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, IL, 60607, USA. xcy@uic.edu.ORCID http://orcid.org/0000-0002-0356-3242

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · UNIVERSITY OF ILLINOIS AT CHICAGO · 1985 to 2025
$3.9M
Differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathyR01EY030842 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jennifer Irene Lim, XINCHENG YAO · 2023 to 2023
$363k
Functional tomography of neurovascular coupling interactions in healthy and diseased retinasR01EY030101 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI XINCHENG YAO · 2022 to 2022
$304k
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY023522NEI NIH HHS R01 EY029673NEI NIH HHS R01 EY030101NEI NIH HHS R01 EY030842U.S. Department of Health & Human Services | NIH | National Eye Institute (NEI) P30EY001792
6 · The paper itself

Abstract

backgroundReliable differentiation of uveal melanoma and choroidal nevi is crucial to guide appropriate treatment, preventing unnecessary procedures for benign lesions and ensuring timely treatment for potentially malignant cases. The purpose of this study is to validate deep learning classification of uveal melanoma and choroidal nevi, and to evaluate the effect of colour fusion options on the classification performance.

methodsA total of 798 ultra-widefield retinal images of 438 patients were included in this retrospective study, comprising 157 patients diagnosed with UM and 281 patients diagnosed with choroidal naevus. Colour fusion options, including early fusion, intermediate fusion and late fusion, were tested for deep learning image classification with a convolutional neural network (CNN). F1-score, accuracy and the area under the curve (AUC) of a receiver operating characteristic (ROC) were used to evaluate the classification performance.

resultsColour fusion options were observed to affect the deep learning performance significantly. For single-colour learning, the red colour image was observed to have superior performance compared to green and blue channels. For multi-colour learning, the intermediate fusion is better than early and late fusion options.

conclusionDeep learning is a promising approach for automated classification of uveal melanoma and choroidal nevi. Colour fusion options can significantly affect the classification performance.

Indexed as

Deep LearningMelanomaUveal NeoplasmsAdultAgedChoroid NeoplasmsColorDiagnosis, DifferentialFemaleHumansMaleMiddle AgedRetrospective StudiesROC CurveUveal Melanoma

Identifiers

PMID38773261
PMCPMC11427558

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.