ArticleBMC complementary medicine and therapies2024
Ethnomedicine, antibacterial activity, antioxidant potential and phytochemical screening of selected medicinal plants in Dibatie district, Metekel zone, western Ethiopia.
Article in BMC complementary medicine and therapies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Medicinal Plants Used for Combating Human Bacterial Diseases in Ethiopia: A Systematic Review.TheScientificWorldJournal · 2026Pooled it
- Phytochemical and Biological Activities ofPlants (Basel, Switzerland) · 2026Article
- Antimicrobial, antioxidant, anticancer, and phytochemical analysis of South African medicinal plants collected from the Senwabarwana area, Limpopo province.BMC complementary medicine and therapies · 2026Article
- Biocontrol Potential of Selected Lamiaceae Species AgainstTheScientificWorldJournal · 2026Article
- Phytochemical and In Vitro Antibacterial Assessment of Selected Wild Edible Plants From Southwestern Ethiopia.International journal of food science · 2026Article
- Network Pharmacology and Computational Study to Identify Active Components and Potential Targets ofCombinatorial chemistry & high throughput screening · 2026Article
- Phytochemical profiling, HPLC analysis, and antimicrobial potential of Curio radicans (L. f.) P.V. Heath.Scientific reports · 2025Article
- Ethnobotanical investigation of medicinal plants utilized by indigenous communities in the Fofa and Toaba sub-districts of the Yem Zone, Central Ethiopian Region.Journal of ethnobiology and ethnomedicine · 2025Article
- Traditionally used phytomedicines and their associated threats in Bita district, southwestern Ethiopia.Journal of ethnobiology and ethnomedicine · 2025Article
- Bioactive chemical composition and pharmacological insights intoFrontiers in molecular biosciences · 2025Review
- Ethnobotanical study of medicinal plants and their threats in Yeki district, Southwestern Ethiopia.Journal of ethnobiology and ethnomedicine · 2024Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundMedicinal plants play a major role in the delivery of healthcare, particularly among the rural population of Ethiopia. Plant extracts and their bioactive compounds have been utilized for the treatment of several diseases. This study was aimed at evaluating the antibacterial activity, antioxidant capacity, and phytochemical content of selected medicinal plants used in Dibatie district, western Ethiopia.
methodsStudy plants were collected, shade dried, pulverized, extracted by maceration in 80% ethanol, and subjected to antibacterial, antioxidant, and phytochemical tests. Minimum inhibitory concentration (MIC) was determined using 96-well microplates and nutrient broth microdilution. Antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay. Phytochemical screening was conducted using standard test methods.
resultsThe ethanolic extract of Polystachya steudneri Rchb.f. pseudobulbs was the most active against gram-negative Proteus mirabilis, Salmonella typhimurium, Klebsiella pneumoniae, Escherichia coli, and Shigella flexneri, with MIC values of 8 ± 0, 11 ± 5, 3 ± 1, 3 ± 1, and 2 ± 0 mg/mL, respectively. The ethanolic extract of P. steudneri was also the most effective against gram-positive Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus agalactiae, and Enterococcus faecalis, with MIC values of 8 ± 0, 8 ± 0, 3 ± 1, and 16 ± 0 mg/mL, respectively. Ethanolic extracts of Gnidia involucrata Steud. ex A.Rich. stems and roots were effective antioxidants, with respective 50% DPPH free radical inhibitory concentrations (IC
conclusionsThis study confirmed the antibiotic, antioxidant, and phytochemical constituents of the investigated plants and suggested further investigations that may lead to bioactive lead compounds.
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