Evidence map›Paper›PMID 38778339›Full record

ArticleParticle and fibre toxicology2024

Combining analytical techniques to assess the translocation of diesel particles across an alveolar tissue barrier in vitro.

Gowsinth Gunasingam, Ruiwen He, Patricia Taladriz-Blanco, Sandor Balog, Alke Petri-Fink, Barbara Rothen-Rutishauser

Erratum issuedAbstract read
In one paragraph

Article in Particle and fibre toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Gowsinth GunasingamAdolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, Fribourg, 1700, Switzerland.
Ruiwen HeAdolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, Fribourg, 1700, Switzerland.
Patricia Taladriz-BlancoAdolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, Fribourg, 1700, Switzerland.
Sandor BalogAdolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, Fribourg, 1700, Switzerland.
Alke Petri-FinkAdolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, Fribourg, 1700, Switzerland.
Barbara Rothen-RutishauserAdolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, Fribourg, 1700, Switzerland. barbara.rothen@unifr.ch.

Funding

H2020 EU project ULtrafine particles from TRansportation- Health Assessment of Source (ULTRHAS)) 955390
6 · The paper itself

Abstract

backgroundDuring inhalation, airborne particles such as particulate matter ≤ 2.5 μm (PM

resultsWe could detect the translocated fraction of DEPs across the PET membranes with 3 μm pore sizes and without cells by TEM analysis, and determine the percentage of translocation at approximatively 37% by UV-VIS (LOD: 1.92 µg.mL

conclusionWe propose a combination of analytical techniques to assess the translocation of DEPs across lung tissues. Our results reveal a low percentage of translocation of DEPs across alveolar epithelial tissue in vitro and they correspond to in vivo findings. The combination approach can be applied to any traffic-generated particles, thus enabling us to understand their involvement in public health.

Indexed as

Particulate MatterPulmonary AlveoliVehicle EmissionsA549 CellsAir PollutantsAlveolar Epithelial CellsHumansMicroscopy, Electron, TransmissionParticle SizePolyethylene TerephthalatesAir PollutantsParticulate MatterPolyethylene TerephthalatesVehicle EmissionsA549 cellsDiesel particles (DEPs)Lock-in thermography (LIT)TranslocationTransmission electron microscopy (TEM)Ultraviolet – visible (UV-VIS)

Identifiers

PMID38778339
PMCPMC11110323

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.