Evidence map›Paper›PMID 38779763›Full record

ReviewJournal of applied physiology (Bethesda, Md. : 1985)2024

Sexual dimorphisms in skeletal muscle: current concepts and research horizons.

Marianne E Emmert, Andrew S Emmert, Qingnian Goh, Roger Cornwall

Abstract readReview
In one paragraph

Review in Journal of applied physiology (Bethesda, Md. : 1985), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marianne E EmmertDivision of Orthopaedic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States.ORCID 0000-0003-3173-9812
Andrew S EmmertDepartment of Orthopaedic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States.ORCID 0000-0002-7381-3315
Qingnian GohDivision of Orthopaedic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States.ORCID 0000-0003-4108-2957
Roger CornwallDivision of Orthopaedic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States.ORCID 0000-0003-2205-2883

Funding

Deciphering the pathophysiology of childhood neuromuscular contracturesR01HD098280 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI CORNWALL, ROGER · 2019 to 2023
$2.0M
Cincinnati Children's Hospital Medical Center (Cincinnati Children's) Division of Orthopaedic Surgery and Junior Cooperative SocietyHHS | National Institutes of Health (NIH) R01HD098280-01NICHD NIH HHS R01 HD098280
6 · The paper itself

Abstract

The complex compositional and functional nature of skeletal muscle makes this organ an essential topic of study for biomedical researchers and clinicians. An additional layer of complexity is added with the consideration of sex as a biological variable. Recent research advances have revealed sexual dimorphisms in developmental biology, muscle homeostasis, adaptive responses, and disorders relating to skeletal muscle. Many of the observed sex differences have hormonal and molecular mechanistic underpinnings, whereas others have yet to be elucidated. Future research is needed to investigate the mechanisms dictating sex-based differences in the various aspects of skeletal muscle. As such, it is necessary that skeletal muscle biologists ensure that both female and male subjects are represented in biomedical and clinical studies to facilitate the successful testing and development of therapeutics for all patients.

Indexed as

Muscle, SkeletalSex CharacteristicsAnimalsFemaleHumansMalemuscle biologymuscle physiologysex as a biological variablesexual dimorphismsskeletal muscle

Identifiers

PMID38779763
PMCPMC11343095

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.