Evidence mapPaperPMID 38780348Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

New Score Models for Predicting Bleeding and Ischemic of Ticagrelor Therapy in Patients with Diabetes Mellitus.

Xiaotong Xia, Shu Chen, Chang Cao, YanRong Ye, Yun Shen

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Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Xiaotong XiaDepartment of Pharmacy, Zhongshan Hospital (Xiamen), Fudan University, Fujian Xiamen, China.ORCID 0000-0002-6247-0118
Shu ChenDepartment of Pharmacy, Zhongshan Hospital (Xiamen), Fudan University, Fujian Xiamen, China.
Chang CaoDepartment of Pharmacy, Zhongshan Hospital (Xiamen), Fudan University, Fujian Xiamen, China.
YanRong YeDepartment of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai, China.
Yun ShenDepartment of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai, China.

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No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTicagrelor is an antiplatelet drug, and its use increases the risk of bleeding. Coronary artery disease is significantly influenced by the widespread occurrence of diabetes mellitus. In order to decrease the incidence of clinical adverse events, a novel bleeding and thrombosis score is developed in this research.

methodsWe conducted a retrospective analysis of patient data from two medical centers who were diagnosed with diabetes mellitus and treated with ticagrelor. We gathered information on every patient from the electronic database of the hospital and follow-up. The collected data were statistically analyzed to obtain risk factors for bleeding and ischemic events.

resultsA total of 851 patients with diabetes mellitus who have been administered ticagrelor are included in our investigation. A total of 76 patients have bleeding events and 80 patients have ischemic events. The analysis of multiple variables indicates that characteristics like the age of >65, having a previous occurrence of bleeding, experiencing anemia, using aspirin, and taking atorvastatin are linked to a higher likelihood of bleeding. Additionally, the age of >65, smoking, having a history of blood clots, and having a BMI ≥ 30 are found to increase the risk of ischemia.

conclusionThe A

Indexed as

HemorrhageTicagrelorAgedDiabetes MellitusFemaleHumansIschemiaMaleMiddle AgedPlatelet Aggregation InhibitorsRetrospective StudiesRisk FactorsThrombosisPlatelet Aggregation InhibitorsTicagrelorbleedingdiabetes mellitusischemicticagrelor

Identifiers

PMID38780348
PMCPMC11119327

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