Evidence map›Paper›PMID 38780885›Full record

ArticleJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology2024

Cornuside ameliorates cognitive impairments via RAGE/TXNIP/NF-κB signaling in Aβ

Wenwen Lian, Zexing Wang, Fulin Zhou, Xiaotang Yuan, Congyuan Xia, Wenping Wang, Yu Yan, Yunchi Cheng, Hua Yang, Jiekun Xu and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  3. Article
  4. Cornuside alleviates cognitive impairments induced by AβAlzheimer's research & therapy · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wenwen Lian *Department of Pharmacy & Institute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China.
Zexing Wang *School of Life Science, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, People's Republic of China.
Fulin ZhouDepartment of Pharmacy & Institute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China.
Xiaotang YuanSchool of Life Science, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, People's Republic of China.
Congyuan XiaDepartment of Pharmacy & Institute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China.
Wenping WangDepartment of Pharmacy & Institute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China.
Yu YanDepartment of Pharmacy & Institute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China.
Yunchi ChengDepartment of Pharmacology, School of Medicine, Yale University, Connecticut, New Haven, USA.
Hua YangSchool of Chemistry and Chemical Engineering, Shaanxi Key Laboratory of Chemical Reaction Engineering, Laboratory of New Energy & New Function Materials, Yan'an University, Yan'an, Shaanxi, 716000, People's Republic of China.
Jiekun XuSchool of Life Science, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, People's Republic of China. xjkbucm@163.com.
Jun HeDepartment of Pharmacy & Institute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China. 15010297582@126.com.
Weiku ZhangDepartment of Pharmacy & Institute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China. cpuzwk@163.com.

Funding

Central Universities Fundamental for Basic Scientific Research of Peking Union Medical College 3332023096Chinese Pharmaceutical Association-Yiling Biomedical Innovation Fund Project CPA-B04-ZC-2021-005Elite Medical Professionals Project of China-Japan Friendship Hospital ZRJY2023-QM10, ZRJY2021-BJ06, ZRJY2021-TD06, ZRJY2021-QM16, ZRJY2023-QM28Key Project Funding for Shaanxi Provincial Natural Science Basic Rearch Program 2022JZ-49National High Level hospital Clinical Research Funding 2023-NHLHCRF-CXYW-01, 2022-NHLHCRF-YNZY-01National Natural Science Foundation of China 82273809, 82273815, 82073731Nonprofit Central Research Institute Fund of Chinese Academy of Medical Science 2022-JKCS-16Yan'an Science and Technology Plan Project 2022SLZDCY-001
6 · The paper itself

Abstract

Cornuside has been discovered to improve learning and memory in AD mice, however, its underlying mechanism was not fully understood. In the present study, we established an AD mice model by intracerebroventricular injection of Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesCognitive DysfunctionNF-kappa BPeptide FragmentsReceptor for Advanced Glycation End ProductsSignal TransductionAnimalsMaleMiceOxidative StressAger protein, mouseAmyloid beta-Peptidesamyloid beta-protein (1-42)NF-kappa BPeptide FragmentsReceptor for Advanced Glycation End ProductsAlzheimer’s diseaseCornusideNeuroinflammationOxidative stressRAGETXNIP

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.