Evidence mapPaperPMID 38784670Full record

ArticleEuropean heart journal supplements : journal of the European Society of Cardiology2024

Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO) scientific statement on the simplification of the drug regimen for secondary cardiovascular prevention.

Leonardo De Luca, Stefania Angela Di Fusco, Gianmarco Iannopollo, Raffaella Mistrulli, Vittoria Rizzello, Alberto Aimo, Alessandro Navazio, Claudio Bilato, Marco Corda, Massimo Di Marco and 11 more

Abstract read
In one paragraph

Article in European heart journal supplements : journal of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Leonardo De LucaDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Viale Camillo Golgi 19, 27100 Pavia, Italy.
Stefania Angela Di FuscoUOC Cardiologia Clinica e Riabilitativa, Presidio Ospedaliero San Filippo Neri-ASL Roma 1, Rome, Italy.ORCID https://orcid.org/0000-0002-8586-9930
Gianmarco IannopolloUOC Cardiologia, Ospedale Maggiore, Bologna, Italy.
Raffaella MistrulliDipartimento di Medicina Clinica e Molecolare, Università degli studi di Roma La Sapienza, Rome, Italy.
Vittoria RizzelloUOC Cardiologia, Ospedale San Giovanni Addolorata, Rome, Italy.
Alberto AimoUOC Cardiologia, Fondazione Toscana Gabriele Monasterio, Pisa, Italy.ORCID https://orcid.org/0000-0001-9129-9519
Alessandro NavazioSOC Cardiologia Ospedaliera, Presidio Ospedaliero Arcispedale Santa Maria Nuova, Azienda USL di Reggio Emilia-IRCCS, Reggio Emilia, Italy.ORCID https://orcid.org/0000-0001-8417-7783
Claudio BilatoUOC Cardiologia, Ospedali dell'Ovest Vicentino, Azienda ULSS 8 Berica, Vicenza, Italy.ORCID https://orcid.org/0000-0003-3474-0579
Marco CordaSC Cardiologia, Azienda Ospedaliera G. Brotzu, Cagliari, Italy.
Massimo Di MarcoU.O.C. Cardiologia-UTIC, Ospedale Santo Spirito, Pescara, Italy.
Giovanna GeraciUOC Cardiologia, Ospedale Sant'Antonio Abate, Trapani, Italy.ORCID https://orcid.org/0000-0003-0092-8717
Attilio IacovoniSSD Chirurgia dei Trapianti e del Trattamento Chirurgico dello Scompenso, Dipartimento Cardiovascolare, ASST Papa Giovanni XXIII, Bergamo, Italy.ORCID https://orcid.org/0000-0003-0347-6672
Massimo MilliCardiologia Firenze 1 (Ospedali S. Maria Nuova e Nuovo San Giovanni di Dio), Azienda USL Toscana Centro, Firenze, Italy.
Vittorio PascaleUTIC-Emodinamica e Cardiologia Interventistica, Ospedale Civile Pugliese, Catanzaro, Italy.
Carmine RiccioU.O.S.D. Follow-up del Paziente Post-Acuto, Dipartimento Cardio-Vascolare, AORN Sant'Anna e San Sebastiano, Caserta, Italy.
Pietro ScicchitanoU.O. Cardiologia-UTIC, Ospedale 'F. Perinei', Altamura, BA, Italy.ORCID https://orcid.org/0000-0003-0471-0053
Emanuele TizzaniDipartimento di Cardiologia, Ospedale degli Infermi, Rivoli, TO, Italy.
Domenico GabrielliDipartimento Cardio-Toraco-Vascolare, U.O.C. Cardiologia, Azienda Ospedaliera San Camillo Forlanini, Roma, Italy.
Massimo GrimaldiU.O.C. Cardiologia-UTIC, Ospedale Miulli, Acquaviva delle Fonti, BA, Italy.ORCID https://orcid.org/0000-0002-9347-8884
Furio ColivicchiUOC Cardiologia Clinica e Riabilitativa, Presidio Ospedaliero San Filippo Neri-ASL Roma 1, Rome, Italy.
Fabrizio OlivaCardiologia 1-Emodinamica, Dipartimento Cardiotoracovascolare "A. De Gasperis", ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The issue of suboptimal drug regimen adherence in secondary cardiovascular prevention presents a significant barrier to improving patient outcomes. To address this, the utilization of drug combinations, specifically single pill combinations (SPCs) and polypills, was proposed as a strategy to simplify treatment regimens. This approach aims to enhance treatment accessibility, affordability, and adherence, thereby reducing healthcare costs and improving patient health. The document is an Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO) scientific statement on simplifying drug regimens for secondary cardiovascular prevention. It discusses the underuse of treatments despite available, effective, and accessible options, highlighting a significant gap in secondary prevention across different socio-economic statuses and countries. The statement explores barriers to implementing evidence-based treatments, including patient, healthcare provider, and system-related challenges. The paper also reviews international guidelines, the role of SPCs and polypills in clinical practice, and their economic impact, advocating for their use in secondary prevention to improve patient outcomes and adherence.

Indexed as

Cardiovascular preventionCardiovascular riskDrug combinationsDrug treatmentPolypillSingle pill combinationTherapeutic adherence

Identifiers

PMID38784670
PMCPMC11110452

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.