Evidence map›Paper›PMID 38787380›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2024

Interaction of macro- and microvascular function underlies brachial artery flow-mediated dilation in humans.

Clare E Thorn, Phillip E Gates, Francesco Casanova, Alessandro Ramalli, Piero Tortoli, Carlo Palombo, Angela C Shore, Kunihiko Aizawa

Abstract readComparative Study
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Clare E ThornDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, United Kingdom.ORCID 0000-0002-7411-6212
Phillip E GatesDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, United Kingdom.
Francesco CasanovaDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, United Kingdom.
Alessandro RamalliDepartment of Information Engineering, University of Florence, Florence, Italy.
Piero TortoliDepartment of Information Engineering, University of Florence, Florence, Italy.ORCID 0000-0002-7984-3128
Carlo PalomboDepartment of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.ORCID 0000-0002-0628-2729
Angela C ShoreDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, United Kingdom.
Kunihiko AizawaDepartment of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, United Kingdom.ORCID 0000-0002-0025-2115

Funding

Innovative Medicine Initiatives IMI/115006
6 · The paper itself

Abstract

Brachial artery flow-mediated dilation (BAFMD) is induced by hyperemic wall shear rate (WSR) following forearm ischemia. In older adults, there appears to be a reduced brachial hyperemic WSR and altered stimulus-response relationship compared with young adults. However, it is unclear if an altered forearm microvascular response to ischemia influences brachial hyperemic WSR in older adults. We determined associations between brachial hyperemic WSR and forearm skeletal muscle oxygen saturation in young and older adults. Healthy young (

Indexed as

Brachial ArteryForearmHyperemiaMicrocirculationMuscle, SkeletalRegional Blood FlowVasodilationAdultAgedAge FactorsAgingBlood Flow VelocityFemaleHumansIschemiaMaleagingblood flowcardiovascularendotheliumoxygenation

Identifiers

PMID38787380
PMCPMC11380966

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.