Evidence map›Paper›PMID 38791128›Full record

ArticleInternational journal of molecular sciences2024

MiR-148a-3p/SIRT7 Axis Relieves Inflammatory-Induced Endothelial Dysfunction.

Camilla Anastasio, Isabella Donisi, Antonino Colloca, Nunzia D'Onofrio, Maria Luisa Balestrieri

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Exosome-based immunotherapy in hepatocellular carcinoma.Clinical and experimental medicine · 2025
    Review
  5. Connecting the Dots: How MicroRNAs Link Asthma and Atherosclerosis.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Immune and Metabolic Mechanisms of Endothelial Dysfunction.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Effects ofNanomaterials (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Camilla AnastasioDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, Via L. De Crecchio 7, 80138 Naples, Italy.
Isabella DonisiDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, Via L. De Crecchio 7, 80138 Naples, Italy.
Antonino CollocaDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, Via L. De Crecchio 7, 80138 Naples, Italy.
Nunzia D'OnofrioDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, Via L. De Crecchio 7, 80138 Naples, Italy.ORCID 0000-0002-5300-9530
Maria Luisa BalestrieriDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, Via L. De Crecchio 7, 80138 Naples, Italy.ORCID 0000-0001-6001-1789

Funding

Italian Ministry of Health-RC IZS ME 09/22Ministero dello Sviluppo Economico F/310110/04/X56Ministero dell'Università e della Ricerca 2022KH87XSMinistero dell'Università e della Ricerca, Next Generation EU P2022SZE5Y
6 · The paper itself

Abstract

In endothelial cells, miR-148a-3p is involved in several pathological pathways, including chronic inflammatory conditions. However, the molecular mechanism of miR-148a-3p in endothelial inflammatory states is, to date, not fully elucidated. To this end, we investigated the involvement of miR-148a-3p in mitochondrial dysfunction and cell death pathways in human aortic endothelial cells (teloHAECs) treated with interleukin-6 (IL-6), a major driver of vascular dysfunction. The results showed that during IL6-activated inflammatory pathways, including increased protein levels of sirtuin 7 (SIRT7) (

Indexed as

ApoptosisEndothelial CellsInflammationMicroRNAsGene Expression RegulationHumansInterleukin-6MitochondriaSignal TransductionSirtuinsInterleukin-6MicroRNAsMIRN148 microRNA, humanSIRT7 protein, humanSirtuinsapoptosisendothelial dysfunctioninflammationmiR-148a-3pmitochondrial damageoxidative stressSIRT7

Identifiers

PMID38791128
PMCPMC11121049

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.