Evidence map›Paper›PMID 38791333›Full record

ReviewInternational journal of molecular sciences2024

Voltage Sensors Embedded in G Protein-Coupled Receptors.

Merav Tauber, Yair Ben-Chaim

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. On Vibronic-Driven Action and Mechanosensitive G Protein-Coupled Receptors.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Merav TauberDepartment of Natural Sciences, The Open University of Israel, Ra'anana 4353701, Israel.
Yair Ben-ChaimDepartment of Natural Sciences, The Open University of Israel, Ra'anana 4353701, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some signaling processes mediated by G protein-coupled receptors (GPCRs) are modulated by membrane potential. In recent years, increasing evidence that GPCRs are intrinsically voltage-dependent has accumulated. A recent publication challenged the view that voltage sensors are embedded in muscarinic receptors. Herein, we briefly discuss the evidence that supports the notion that GPCRs themselves are voltage-sensitive proteins and an alternative mechanism that suggests that voltage-gated sodium channels are the voltage-sensing molecules involved in such processes.

Indexed as

Receptors, G-Protein-CoupledVoltage-Gated Sodium ChannelsAnimalsHumansMembrane PotentialsSignal TransductionReceptors, G-Protein-CoupledVoltage-Gated Sodium ChannelsG protein coupled receptorsmuscarinic receptorvoltage dependencevoltage sensor

Identifiers

PMID38791333
PMCPMC11120775

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.