Evidence mapPaperPMID 38791465Full record

ArticleInternational journal of molecular sciences2024

Plasma Proteins Associated with COVID-19 Severity in Puerto Rico.

Lester J Rosario-Rodríguez, Yadira M Cantres-Rosario, Kelvin Carrasquillo-Carrión, Alexandra Rosa-Díaz, Ana E Rodríguez-De Jesús, Verónica Rivera-Nieves, Eduardo L Tosado-Rodríguez, Loyda B Méndez, Abiel Roche-Lima, Jorge Bertrán and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lester J Rosario-RodríguezDepartment of Microbiology and Medical Zoology, University of Puerto Rico, Medical Sciences Campus, San Juan 00935, Puerto Rico.ORCID 0000-0003-1004-152X
Yadira M Cantres-RosarioTranslational Proteomics Center, Research Capacity Core, Center for Collaborative Research in Health Disparities, University of Puerto Rico, Medical Sciences Campus, San Juan 00935, Puerto Rico.
Kelvin Carrasquillo-CarriónIntegrated Informatics, Research Capacity Core, Center for Collaborative Research in Health Disparities, University of Puerto Rico, Medical Sciences Campus, San Juan 00935, Puerto Rico.ORCID 0000-0001-7224-2349
Alexandra Rosa-DíazInterdisciplinary Studies, Natural Sciences, University of Puerto Rico, Río Piedras Campus, San Juan 00925, Puerto Rico.ORCID 0009-0001-1335-6714
Ana E Rodríguez-De JesúsTranslational Proteomics Center, Research Capacity Core, Center for Collaborative Research in Health Disparities, University of Puerto Rico, Medical Sciences Campus, San Juan 00935, Puerto Rico.
Verónica Rivera-NievesInterdisciplinary Studies, Natural Sciences, University of Puerto Rico, Río Piedras Campus, San Juan 00925, Puerto Rico.
Eduardo L Tosado-RodríguezIntegrated Informatics, Research Capacity Core, Center for Collaborative Research in Health Disparities, University of Puerto Rico, Medical Sciences Campus, San Juan 00935, Puerto Rico.ORCID 0000-0002-9140-8671
Loyda B MéndezDepartment of Science & Technology, Ana G. Mendez University, Carolina 00928, Puerto Rico.ORCID 0000-0002-3439-8315
Abiel Roche-LimaIntegrated Informatics, Research Capacity Core, Center for Collaborative Research in Health Disparities, University of Puerto Rico, Medical Sciences Campus, San Juan 00935, Puerto Rico.ORCID 0000-0003-2246-6744
Jorge BertránInfectious Diseases, Auxilio Mutuo Hospital, San Juan 00919, Puerto Rico.
Loyda M MeléndezDepartment of Microbiology and Medical Zoology, University of Puerto Rico, Medical Sciences Campus, San Juan 00935, Puerto Rico.ORCID 0000-0003-2571-8206

Funding

Science and Technology Competency and Education CoreP20GM103475 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · 2021 to 2025
$11.8M
The Microbiome as a risk factor for hr-HPV persistence and Cervical CancerU54MD007600 · UNIVERSITY OF PUERTO RICO MED SCIENCES · 2025 to 2025
$3.5M
CSRD VA 1National Institute of Minority Health and Health Disparities (NIMHHD) U54MD007600NIGMS NIH HHS P20GM103475NINDS NIH HHS F99NS11345NINDS NIH HHS K00NS11345
6 · The paper itself

Abstract

Viral strains, age, and host factors are associated with variable immune responses against SARS-CoV-2 and disease severity. Puerto Ricans have a genetic mixture of races: European, African, and Native American. We hypothesized that unique host proteins/pathways are associated with COVID-19 disease severity in Puerto Rico. Following IRB approval, a total of 95 unvaccinated men and women aged 21-71 years old were recruited in Puerto Rico from 2020-2021. Plasma samples were collected from COVID-19-positive subjects (

Indexed as

COVID-19ProteomicsSARS-CoV-2Severity of Illness IndexAdultAgedBlood ProteinsCytokinesFemaleHumansMaleMiddle AgedPuerto RicoTandem Mass SpectrometryYoung AdultBlood ProteinsCytokinescadherin-13COVID-19H-cadherinproteomicsPuerto RicoSARS-CoV-2T-cadherinTNF-α

Identifiers

PMID38791465
PMCPMC11121485

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.