Evidence map›Paper›PMID 38794208›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Concomitant Treatment with Doxycycline and Rifampicin in Balb/c Mice Infected with

José Luis Maldonado-García, Samantha Alvarez-Herrera, Gilberto Pérez-Sánchez, Enrique Becerril-Villanueva, Lenin Pavón, Emiliano Tesoro-Cruz, Manuel Iván Girón-Pérez, Gabriela Hurtado-Alvarado, Gabriela Damián-Morales, Rubén López-Santiago and 1 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Reactivation of hidden-latentAntimicrobial agents and chemotherapy · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

José Luis Maldonado-GarcíaLaboratorio de Inmunología Celular, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0003-2694-1290
Samantha Alvarez-HerreraLaboratorio de Psicoinmunología, Dirección de Investigaciones en Neurociencias del Instituto Nacional de Psiquiatría Ramón de la Fuente, Mexico City 14370, Mexico.ORCID 0000-0001-9747-885X
Gilberto Pérez-SánchezLaboratorio de Psicoinmunología, Dirección de Investigaciones en Neurociencias del Instituto Nacional de Psiquiatría Ramón de la Fuente, Mexico City 14370, Mexico.ORCID 0000-0003-3878-0631
Enrique Becerril-VillanuevaLaboratorio de Psicoinmunología, Dirección de Investigaciones en Neurociencias del Instituto Nacional de Psiquiatría Ramón de la Fuente, Mexico City 14370, Mexico.
Lenin PavónLaboratorio de Psicoinmunología, Dirección de Investigaciones en Neurociencias del Instituto Nacional de Psiquiatría Ramón de la Fuente, Mexico City 14370, Mexico.
Emiliano Tesoro-CruzUnidad de Investigación Biomédica en Inmunología e Infectología, Hospital de Infectología, Centro Médico Nacional "La Raza", IMSS, Mexico City 02990, Mexico.
Manuel Iván Girón-PérezLaboratorio Nacional LANIIA-Nayarit, Universidad Autónoma de Nayarit, Tepic 63173, Mexico.ORCID 0000-0001-6808-6590
Gabriela Hurtado-AlvaradoDepartamento de Anatomía, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04360, Mexico.
Gabriela Damián-MoralesLaboratorio de Inmunología Celular, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City 11340, Mexico.
Rubén López-SantiagoLaboratorio de Inmunología Celular, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0003-3629-3813
Martha C Moreno-LafontLaboratorio de Inmunología Celular, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City 11340, Mexico.

Funding

Consejo Nacional de Humanidades, Ciencias y Tecnologías 594780Consejo Nacional de Humanidades, Ciencias y Tecnologías 822954Escuela Nacional de Ciencias Biológicas SIP 20181218Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz NC23189.0
6 · The paper itself

Abstract

Brucellosis is an infection widely distributed around the world, and in some countries it is considered a public health problem. Brucellosis causes insidious symptoms that make it difficult to diagnose. Infection can also trigger chronic pain and neuropsychiatric complications. Antibiotics are not always effective to eradicate infection, contributing to chronicity. We aimed to investigate the effects of antibiotic treatment on proinflammatory cytokines, neurotransmitters, corticosterone, and behavior in a murine model of infecrion of

Indexed as

behavioral testbrucellosisdoxycyclineinflammatory responseneurotransmittersrifampicin

Identifiers

PMID38794208
PMCPMC11123987

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.