Evidence mapPaperPMID 38796183Full record

Observational studyRMD open2024

Natural language processing to identify and characterize spondyloarthritis in clinical practice.

Diego Benavent, María Benavent-Núñez, Judith Marin-Corral, Javier Arias-Manjón, Victoria Navarro-Compán, Miren Taberna, Ignacio Salcedo, Diana Peiteado, Loreto Carmona, Eugenio de Miguel and 1 more

Abstract readObservational Study
In one paragraph

Observational study in RMD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Diego BenaventSavana Research S.L, Madrid, Spain d_benavent@hotmail.com.ORCID 0000-0001-9119-5330
María Benavent-NúñezSavana Research S.L, Madrid, Spain.ORCID 0000-0002-9248-748X
Judith Marin-CorralSavana Research S.L, Madrid, Spain.ORCID 0000-0003-1320-4427
Javier Arias-ManjónMedsavana S.L, Madrid, Spain.ORCID 0009-0008-3852-4092
Victoria Navarro-CompánRheumatology, Hospital Universitario La Paz, Madrid, Spain.ORCID 0000-0002-4527-852X
Miren TabernaSavana Research S.L, Madrid, Spain.ORCID 0000-0002-2446-186X
Ignacio SalcedoMedsavana S.L, Madrid, Spain.
Diana PeiteadoRheumatology, Hospital Universitario La Paz, Madrid, Spain.ORCID 0000-0002-6953-409X
Loreto CarmonaInstituto de Salud Musculoesquelética, Madrid, Spain.ORCID 0000-0002-4401-2551
Eugenio de MiguelRheumatology, Hospital Universitario La Paz, Madrid, Spain.ORCID 0000-0001-5146-1964
Savana Research group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to use a novel technology based on natural language processing (NLP) to extract clinical information from electronic health records (EHRs) to characterise the clinical profile of patients diagnosed with spondyloarthritis (SpA) at a large-scale hospital.

methodsAn observational, retrospective analysis was conducted on EHR data from all patients with SpA (including psoriatic arthritis (PsA)) at Hospital Universitario La Paz, between 2020 and 2022. Data were collected using Savana Manager, an NLP-based system, enabling the extraction of information from unstructured, free-text EHRs. Variables analysed included demographic data, SpA subtypes, comorbidities and treatments. The performance of the technology in detecting SpA clinical entities was evaluated through precision, recall and F-1 score metrics.

resultsFrom a hospital population of 639 474 patients, 4337 (0.7%) patients had a diagnosis of SpA or their subtypes in their EHR. The population predominantly comprised men (55.3%) with a mean age of 50.9 years. Peripheral SpA (including PsA) was reported in 31.6%, axial SpA in 20.9%, both axial and peripheral SpA in 3.7%, while 43.7% of patients did not have the SpA subtype reported. Common comorbidities included hypertension (25.0%), dyslipidaemia (22.2%) and diabetes mellitus (15.5%). The use of conventional disease-modifying antirheumatic drugs (csDMARDs) and biological DMARDs (bDMARDs) was documented, with methotrexate (25.3% of patients) being the most used csDMARDs and adalimumab (10.6% of patients) the most used bDMARD. The NLP technology demonstrated high precision and recall, with all the assessed F-1 score values over 0.80, indicating reliable data extraction.

conclusionThe application of NLP technology facilitated the characterisation of the SpA patient profile, including demographics, clinical features, comorbidities and treatments. This study supports the utility of NLP in enhancing the understanding of SpA and suggests its potential for improving patient management by extracting meaningful information from unstructured EHR data.

Indexed as

Electronic Health RecordsNatural Language ProcessingSpondylarthritisAdultAntirheumatic AgentsArthritis, PsoriaticComorbidityFemaleHumansMaleMiddle AgedRetrospective StudiesAntirheumatic AgentsMachine LearningOutcome Assessment, Health CareSpondyloarthritis

Identifiers

PMID38796183
PMCPMC11129039

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.