Evidence map›Paper›PMID 38798648›Full record

ArticlebioRxiv : the preprint server for biology2024

RosetteArray

Brady F Lundin, Gavin T Knight, Nikolai J Fedorchak, Kevin Krucki, Nisha Iyer, Jack E Maher, Nicholas R Izban, Abilene Roberts, Madeline R Cicero, Joshua F Robinson and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Brady F LundinDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53705, USA.
Gavin T KnightWisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI 53715, USA.
Nikolai J FedorchakNeurosetta LLC, 330 N. Orchard Street Rm 4140A, Madison, WI 53715 USA.
Kevin KruckiNeurosetta LLC, 330 N. Orchard Street Rm 4140A, Madison, WI 53715 USA.
Nisha IyerDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0002-9597-0936
Jack E MaherWisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI 53715, USA.
Nicholas R IzbanWisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI 53715, USA.
Abilene RobertsWisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI 53715, USA.
Madeline R CiceroWisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI 53715, USA.
Joshua F RobinsonCenter of Reproductive Sciences, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, CA 94143, USA.
Bermans J IskandarDepartment of Neurological Surgery, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, WI 53705, USA.
Rebecca WillettNeurosetta LLC, 330 N. Orchard Street Rm 4140A, Madison, WI 53715 USA.
Randolph S AshtonDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0002-6842-7022

Funding

Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI POLLAK, SETH D · 2016 to 2020
$6.0M
Development and Evaluation of Rosette Array Technology for HumanNeurodevelopmental Toxicity ScreeningR42ES033912 · NIEHS · NEUROSETTA LLC · PI ASHTON, RANDOLPH SCOTT · 2022 to 2023
$1.7M
Human Microphysiological Model of Afferent Nociceptive SignalingUG3TR003150 · NCATS · TULANE UNIVERSITY OF LOUISIANA · PI ASHTON, RANDOLPH S, MOORE, MICHAEL J · 2019 to 2019
$1.2M
Evaluating Human Pluripotent Stem Cell-Derived Neural Rosette Arrays as a Neural Tube Defect Risk Screening PlatformR21HD103111 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI ASHTON, RANDOLPH S · 2021 to 2022
$427k
NCATS NIH HHS UG3 TR003150NICHD NIH HHS R21 HD103111NICHD NIH HHS U54 HD090256NIEHS NIH HHS R42 ES033912
6 · The paper itself

Abstract

Neural organoids have revolutionized how human neurodevelopmental disorders (NDDs) are studied. Yet, their utility for screening complex NDD etiologies and in drug discovery is limited by a lack of scalable and quantifiable derivation formats. Here, we describe the RosetteArray

Identifiers

PMID38798648
PMCPMC11118315

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.