Evidence map›Paper›PMID 38799322›Full record

ReviewACS omega2024

Maggot Kinase and Natural Thrombolytic Proteins.

Can Liu, Kaixin Zhang, Shihao Zhang, Xin Li, Huiting Sun, Lanqing Ma

Abstract readReview
In one paragraph

Review in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Can LiuKey Laboratory for Northern Urban Agriculture of Ministry of Agriculture and Rural Affairs of China, Beijing University of Agriculture, Beijing 102206, PR China.ORCID https://orcid.org/0000-0002-2036-0826
Kaixin ZhangKey Laboratory for Northern Urban Agriculture of Ministry of Agriculture and Rural Affairs of China, Beijing University of Agriculture, Beijing 102206, PR China.
Shihao ZhangKey Laboratory for Northern Urban Agriculture of Ministry of Agriculture and Rural Affairs of China, Beijing University of Agriculture, Beijing 102206, PR China.
Xin LiKey Laboratory for Northern Urban Agriculture of Ministry of Agriculture and Rural Affairs of China, Beijing University of Agriculture, Beijing 102206, PR China.
Huiting SunKey Laboratory for Northern Urban Agriculture of Ministry of Agriculture and Rural Affairs of China, Beijing University of Agriculture, Beijing 102206, PR China.
Lanqing MaKey Laboratory for Northern Urban Agriculture of Ministry of Agriculture and Rural Affairs of China, Beijing University of Agriculture, Beijing 102206, PR China.ORCID https://orcid.org/0000-0002-5578-6958

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombolytic enzymes constitute a class of proteases with antithrombotic functions. Derived from natural products and abundant in nature, certain thrombolytic enzymes, such as urokinase, earthworm kinase, and streptokinase, have been widely used in the clinical treatment of vascular embolic diseases. Fly maggots, characterized by their easy growth and low cost, are a traditional Chinese medicine recorded in the Compendium of Materia Medica. These maggots can also be used as raw material for the extraction and preparation of thrombolytic enzymes (maggot kinase). In this review, we assembled global research reports on natural thrombolytic enzymes through a literature search and reviewed the functions and structures of natural thrombolytic enzymes to provide a reference for natural thrombophilic drug screening and development.

Identifiers

PMID38799322
PMCPMC11112594

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.