Evidence map›Paper›PMID 38802352›Full record

ArticleNature communications2024

Acute and post-acute respiratory complications of SARS-CoV-2 infection: population-based cohort study in South Korea and Japan.

Yujin Choi, Hyeon Jin Kim, Jaeyu Park, Myeongcheol Lee, Sunyoung Kim, Ai Koyanagi, Lee Smith, Min Seo Kim, Masoud Rahmati, Hayeon Lee and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Article
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  3. Association between residential greenness and the risk of inflammatory bowel disease in patients with COVID-19: A Korean nationwide cohort study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yujin Choi *Center for Digital Health, Medical Science research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.ORCID http://orcid.org/0009-0002-4131-712X
Hyeon Jin Kim *Center for Digital Health, Medical Science research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.
Jaeyu Park *Center for Digital Health, Medical Science research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.
Myeongcheol LeeCenter for Digital Health, Medical Science research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.
Sunyoung KimDepartment of Family Medicine, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.
Ai KoyanagiResearch and Development Unit, Parc Sanitari Sant Joan de Deu, Barcelona, Spain.
Lee SmithCentre for Health, Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.ORCID http://orcid.org/0000-0002-5340-9833
Min Seo KimCardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-2115-7835
Masoud RahmatiCEReSS Health Service Research and Quality of Life Center, Assistance Publique-Hôpitaux de Marseille, Aix-Marseille University, Marseille, France.ORCID http://orcid.org/0000-0003-4792-027X
Hayeon LeeCenter for Digital Health, Medical Science research Institute, Kyung Hee University College of Medicine, Seoul, South Korea. wwhy28@khu.ac.kr.ORCID http://orcid.org/0009-0000-2403-6241
Jiseung KangDivision of Sleep Medicine, Harvard Medical School, Boston, MA, USA. wltmd1006@gmail.com.ORCID http://orcid.org/0000-0002-3734-7572
Dong Keon YonCenter for Digital Health, Medical Science research Institute, Kyung Hee University College of Medicine, Seoul, South Korea. yonkkang@gmail.com.ORCID http://orcid.org/0000-0003-1628-9948

Funding

Korea Health Industry Development Institute (KHIDI) HV22C0233Ministry of Food and Drug Safety (MFDS) 21153MFDS601
6 · The paper itself

Abstract

Considering the significant burden of post-acute COVID-19 conditions among patients infected with SARS-CoV-2, we aimed to identify the risk of acute respiratory complications or post-acute respiratory sequelae. A binational population-based cohort study was conducted to analyze the risk of acute respiratory complications or post-acute respiratory sequelae after SARS-CoV-2 infection. We used a Korean nationwide claim-based cohort (K-COV-N; n = 2,312,748; main cohort) and a Japanese claim-based cohort (JMDC; n = 3,115,606; replication cohort) after multi-to-one propensity score matching. Among 2,312,748 Korean participants (mean age, 47.2 years [SD, 15.6]; 1,109,708 [48.0%] female), 17.1% (394,598/2,312,748) were infected with SARS-CoV-2. The risk of acute respiratory complications or post-acute respiratory sequelae is significantly increased in people with SARS-CoV-2 infection compared to the general population (acute respiratory complications: HR, 8.06 [95% CI, 6.92-9.38]; post-acute respiratory sequelae: 1.68 [1.62-1.75]), and the risk increased with increasing COVID-19 severity. We identified COVID-19 vaccination as an attenuating factor, showing a protective association against acute or post-acute respiratory conditions. Furthermore, while the excess post-acute risk diminished with time following SARS-CoV-2 infection, it persisted beyond 6 months post-infection. The replication cohort showed a similar pattern in the association. Our study comprehensively evaluates respiratory complications in post-COVID-19 conditions, considering attenuating factors such as vaccination status, post-infection duration, COVID-19 severity, and specific respiratory conditions.

Indexed as

COVID-19SARS-CoV-2AdultAgedCohort StudiesFemaleHumansJapanMaleMiddle AgedPost-Acute COVID-19 SyndromeRepublic of KoreaRisk Factors

Identifiers

PMID38802352
PMCPMC11130304

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.