Evidence map›Paper›PMID 38806699›Full record

ArticleEye (London, England)2024

The UK clinical eye research strategy: refreshing research priorities for clinical eye research in the UK.

Rupert R A Bourne, Malik Moledina, Augusto Azuara-Blanco, George M Saleh, James E Self, Sobha Sivaprasad, Srilakshmi M Sharma, Andrew Ross, Rose M Gilbert, Maram E A Abdalla Elsayed and 18 more

Abstract read
In one paragraph

Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Minimally invasive trabecular meshwork surgery for open-angle glaucoma.The Cochrane database of systematic reviews · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Rupert R A BourneVision and Eye Research Institute, School of Medicine, Anglia Ruskin University, Cambridge, UK. rb@rupertbourne.co.uk.ORCID http://orcid.org/0000-0002-8169-1645
Malik MoledinaImperial College NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0003-3554-7797
Augusto Azuara-BlancoCentre for Public Health, Queen's University Belfast, Belfast, UK.ORCID http://orcid.org/0000-0002-4805-9322
George M SalehResearch, Cataract and Adnexal Dept, Moorfields Eye Hospital, London, UK.
James E SelfUniversity of Southampton, Southampton, UK.ORCID http://orcid.org/0000-0002-1030-9963
Sobha SivaprasadNIHR Moorfields Clinical Research Facility, Moorfields Eye Hospital, London, UK.
Srilakshmi M SharmaDept of Ophthalmology, Oxford Eye Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.
Andrew RossDepartment of Ophthalmology, Cambridge University Hospitals, Cambridge, UK.
Rose M GilbertDepartment of Ophthalmology, Cambridge University Hospitals, Cambridge, UK.ORCID http://orcid.org/0000-0002-9115-1220
Maram E A Abdalla ElsayedDept of Ophthalmology, Oxford Eye Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.
Won Young MoonDept of Ophthalmology, Oxford Eye Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.
Manjo DougVision and Eye Research Institute, School of Medicine, Anglia Ruskin University, Cambridge, UK.
Pádraig J MulhollandNIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.ORCID http://orcid.org/0000-0001-5166-0592
Alexander C DayNIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Vito RomanoDepartment of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.ORCID http://orcid.org/0000-0002-5148-7643
Geraldine V HoadMacular Society, Andover, UK.ORCID http://orcid.org/0000-0002-6881-6781
Madina KaraFight for Sight, London, UK.
Ailish MurrayMoorfields Eye Charity, Moorfields Eye Hospital, London, UK.
Louise GowEye care and living well services, Royal National Institute of Blind people, London, UK.
Faruque GhanchiBradford Teaching Hospitals, Royal Infirmary, Bradford, West Yorkshire, UK.ORCID http://orcid.org/0000-0002-4448-8162
Praveen J PatelNIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.ORCID http://orcid.org/0000-0001-8682-4067
Richard P GaleYork Hospital, University of York, York, UK.
Christiana DinahDepartment of Ophthalmology, London North West University Healthcare NHS Trust, London, UK.ORCID http://orcid.org/0000-0002-0815-4771
Keith ValentineFight for Sight, London, UK.
Cathy YelfMacular Society, Andover, UK.
Vanessa PoustieNIHR Clinical Research Network, University of Liverpool, Liverpool, UK.
NIHR Ophthalmology Specialty Group
Executive Group of UK Clinical Eye Research Strategy

Funding

Fight for Sight UK N/AMacular Society N/AWellcome Trust
6 · The paper itself

Abstract

objectivesTo validate and update the 2013 James Lind Alliance (JLA) Sight Loss and Vision Priority Setting Partnership (PSP)'s research priorities for Ophthalmology, as part of the UK Clinical Eye Research Strategy.

methodsTwelve ophthalmology research themes were identified from the JLA report. They were allocated to five Clinical Study Groups of diverse stakeholders who reviewed the top 10 research priorities for each theme. Using an online survey (April 2021-February 2023), respondents were invited to complete one or more of nine subspecialty surveys. Respondents indicated which of the research questions they considered important and subsequently ranked them.

resultsIn total, 2240 people responded to the survey (mean age, 59.3 years), from across the UK. 68.1% were female. 68.2% were patients, 22.3% healthcare professionals or vision researchers, 7.1% carers, and 2.1% were charity support workers. Highest ranked questions by subspecialty: Cataract (prevention), Cornea (improving microbial keratitis treatment), Optometric (impact of integration of ophthalmic primary and secondary care via community optometric care pathways), Refractive (factors influencing development and/or progression of refractive error), Childhood onset (improving early detection of visual disorders), Glaucoma (effective and improved treatments), Neuro-ophthalmology (improvements in prevention, diagnosis and treatment of neurodegeneration affecting vision), Retina (improving prevention, diagnosis and treatment of dry age-related macular degeneration), Uveitis (effective treatments for ocular and orbital inflammatory diseases).

conclusionsA decade after the initial PSP, the results refocus the most important research questions for each subspecialty, and prime targeted research proposals within Ophthalmology, a chronically underfunded specialty given the substantial burden of disability caused by eye disease.

Indexed as

Biomedical ResearchOphthalmologyAdultAgedEye DiseasesFemaleHealth PrioritiesHumansMaleMiddle AgedSurveys and QuestionnairesUnited Kingdom

Identifiers

PMID38806699
PMCPMC11226710

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.