Evidence map›Paper›PMID 38810215›Full record

ArticleACS infectious diseases2024

Understanding the Antiplasmodial Action of Resistance-Refractory Xanthoquinodin A1.

Jennifer E Collins, Tiantian Jiang, Jin Woo Lee, Karen Wendt, Flore Nardella, Jin Jeon, Raphaella Paes, Natalia Mojica Santos, Frances Rocamora, Maya Chang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Fungal-derived methyldeoxaphomins targetProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jennifer E CollinsDivision of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, 12722 Research Parkway, Orlando, Florida 32826, United States.
Tiantian JiangDepartment of Pediatrics, School of Medicine, University of California San Diego, La Jolla, California 92093, United States.
Jin Woo LeeCollege of Pharmacy, Duksung Women's University, Seoul 01369, Republic of Korea.ORCID 0000-0002-0573-0884
Karen WendtDepartment of Chemistry and Biochemistry, Institute for Natural Products Applications & Research Technologies, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma 73019, United States.
Flore NardellaDivision of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, 12722 Research Parkway, Orlando, Florida 32826, United States.
Jin JeonDepartment of Microbiology and Immunology, Columbia University Irving Medical Center, New York, New York 10032, United States.
Raphaella PaesDivision of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, 12722 Research Parkway, Orlando, Florida 32826, United States.ORCID 0000-0002-6146-5309
Natalia Mojica SantosDivision of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, 12722 Research Parkway, Orlando, Florida 32826, United States.ORCID 0000-0003-1892-1628
Frances RocamoraDepartment of Pediatrics, School of Medicine, University of California San Diego, La Jolla, California 92093, United States.
Maya ChangDepartment of Pediatrics, School of Medicine, University of California San Diego, La Jolla, California 92093, United States.
Samuel SchaeferDepartment of Pediatrics, School of Medicine, University of California San Diego, La Jolla, California 92093, United States.
Robert H CichewiczDepartment of Chemistry and Biochemistry, Institute for Natural Products Applications & Research Technologies, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma 73019, United States.ORCID 0000-0003-0744-4117
Elizabeth A WinzelerDepartment of Pediatrics, School of Medicine, University of California San Diego, La Jolla, California 92093, United States.ORCID 0000-0002-4049-2113
Debopam ChakrabartiDivision of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, 12722 Research Parkway, Orlando, Florida 32826, United States.ORCID 0000-0002-4554-3119

Funding

Novel Antimalarials from FungiR01AI154777 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI CHAKRABARTI, DEBOPAM, CICHEWICZ, ROBERT HENRY · 2020 to 2024
$3.8M
NIAID NIH HHS R01 AI154777
6 · The paper itself

Abstract

Our previous work identified a series of 12 xanthoquinodin analogues and 2 emodin-dianthrones with broad-spectrum activities against

Indexed as

AntimalarialsDrug ResistancePlasmodium bergheiPlasmodium falciparumToxoplasmaAnimalsAnthraquinonesHumansAnthraquinonesAntimalarialsXanthoquinodin, Fungal derived, Plasmodium, malaria, antiplasmodial

Identifiers

PMID38810215
PMCPMC11533362

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.