Evidence map›Paper›PMID 38811627›Full record

ArticleScientific reports2024

PET/MRI multimodality imaging to evaluate changes in glymphatic system function and biomarkers of Alzheimer's disease.

Hidehiko Okazawa, Munenobu Nogami, Shota Ishida, Akira Makino, Tetsuya Mori, Yasushi Kiyono, Masamichi Ikawa

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. White matterAlzheimer's research & therapy · 2026
    Article
  10. Article
  11. G-ALPS: An index for evaluating cognitive decline and aging using diffusion tensor imaging.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hidehiko OkazawaBiomedical Imaging Research Center, University of Fukui, 23-3, Matsuoka-Shimaizuki, Eiheiji-cho, Fukui, 910-1193, Japan. okazawa@u-fukui.ac.jp.ORCID 0000-0001-7046-3383
Munenobu NogamiBiomedical Imaging Research Center, University of Fukui, 23-3, Matsuoka-Shimaizuki, Eiheiji-cho, Fukui, 910-1193, Japan.
Shota IshidaKyoto College of Medical Science, Nantan, Japan.
Akira MakinoBiomedical Imaging Research Center, University of Fukui, 23-3, Matsuoka-Shimaizuki, Eiheiji-cho, Fukui, 910-1193, Japan.
Tetsuya MoriBiomedical Imaging Research Center, University of Fukui, 23-3, Matsuoka-Shimaizuki, Eiheiji-cho, Fukui, 910-1193, Japan.
Yasushi KiyonoBiomedical Imaging Research Center, University of Fukui, 23-3, Matsuoka-Shimaizuki, Eiheiji-cho, Fukui, 910-1193, Japan.
Masamichi IkawaBiomedical Imaging Research Center, University of Fukui, 23-3, Matsuoka-Shimaizuki, Eiheiji-cho, Fukui, 910-1193, Japan.

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) 18H02763MEXT | Japan Society for the Promotion of Science (JSPS) 22H03017MEXT | Japan Society for the Promotion of Science (JSPS) 23K06924
6 · The paper itself

Abstract

The glymphatic system is considered to play a pivotal role in the clearance of disease-causing proteins in neurodegenerative diseases. This study employed MR diffusion tensor imaging (DTI) to evaluate glymphatic system function and its correlation with brain amyloid accumulation levels measured using [

Indexed as

Alzheimer DiseaseBiomarkersCognitive DysfunctionGlymphatic SystemMagnetic Resonance ImagingMultimodal ImagingPositron-Emission TomographyAgedAged, 80 and overAniline CompoundsBrainDiffusion Tensor ImagingFemaleHumansMaleMiddle Aged2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazoleAniline CompoundsBiomarkersThiazolesAlzheimer’s diseaseAmyloid imagingDTI-ALPSGlymphatic systemPET/MRI

Identifiers

PMID38811627
PMCPMC11137097

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.