Evidence map›Paper›PMID 38812752›Full record

ArticleFrontiers in cellular and infection microbiology2024

Structural and functional alteration of the gut microbiota in elderly patients with hyperlipidemia.

Meng Xia, Yafang Xu, Huajun Li, Juan Huang, Haolin Zhou, Chuanzhou Gao, Jingyi Han

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Gut microbial alterations and functional shifts in patients with hypertriglyceridemia: insights from a northwestern Chinese metagenomic study.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meng XiaDepartment of Clinical Laboratory, First Affiliated Hospital, Dalian Medical University, Dalian, China.
Yafang XuDepartment of Microecology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Huajun LiDepartment of Microecology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Juan HuangDepartment of Microecology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Haolin ZhouDepartment of Microecology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Chuanzhou GaoInstitute of Cancer Stem Cell, Dalian Medical University, Dalian, China.
Jingyi HanDepartment of Clinical Laboratory, First Affiliated Hospital, Dalian Medical University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the structure, composition, and functions of the gut microbiota in elderly patients with hyperlipidemia. Methods: Sixteen older patients diagnosed with hyperlipidemia (M group) and 10 healthy, age-matched normal volunteers (N group) were included. These groups were further subdivided by sex into the male normal (NM, n = 5), female normal (NF, n = 5), male hyperlipidemia (MM, n = 8), and female hyperlipidemia (MF, n = 8) subgroups. Stool samples were collected for high-throughput sequencing of 16S rRNA genes. Blood samples were collected for clinical biochemical index testing. Results: Alpha- and beta-diversity analyses revealed that the structure and composition of the gut microbiota were significantly different between the M and N groups. The relative abundances of

Indexed as

BacteriaFecesGastrointestinal MicrobiomeHyperlipidemiasRNA, Ribosomal, 16SAgedAged, 80 and overFemaleHigh-Throughput Nucleotide SequencingHumansMaleMiddle AgedRNA, Ribosomal, 16S16S rRNA gene high throughput sequencingelderly peoplegut microbiotahyperlipidemialipid metabolism

Identifiers

PMID38812752
PMCPMC11133514

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.